{"id":"W2095003522","doi":"10.1016/j.bmcl.2004.12.015","title":"Synthesis of half-mustard combi-molecules with fluorescence properties: correlation with EGFR status","year":2005,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital; McGill University","funders":"National Cancer Institute","keywords":"Chemistry; Fluorescence; Flow cytometry; Tyrosine kinase; DNA; Cell culture; Biophysics; Biochemistry; Molecular biology; Signal transduction; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001038218,0.000333052,0.000381103,0.00003143971,0.000123624,0.00002452037,0.0003443784,0.0001257299,0.00092383],"category_scores_gemma":[0.00009616611,0.0002422802,0.00006109637,0.0002237816,0.0004912976,0.0001004454,0.00003977126,0.000288748,0.00002392502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001984412,"about_ca_system_score_gemma":0.0001863123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009437039,"about_ca_topic_score_gemma":0.00001003945,"domain_scores_codex":[0.9980391,0.00001490579,0.0004212912,0.0004780898,0.0005916907,0.0004549727],"domain_scores_gemma":[0.9986442,0.0001121023,0.0003167037,0.000597836,0.0001201371,0.0002090444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001860646,0.0001617854,0.002013723,0.0003884021,0.00009334735,0.00001287711,0.0002638137,0.00005736575,0.9934417,0.000013748,0.0004791914,0.002887994],"study_design_scores_gemma":[0.0006145345,0.00002336593,0.0004966077,0.0006741669,0.0001916932,0.00007711641,0.0008534816,0.0003560502,0.9934916,0.000001245021,0.002887189,0.0003328995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905818,0.0002538818,0.0008293693,0.00511977,0.00001180961,0.0001325451,0.00002736188,0.0001136001,0.00292983],"genre_scores_gemma":[0.9973397,0.000041417,0.00186831,0.0001990993,0.0002318277,0.00006943133,0.00003363584,0.00005652387,0.0001600782],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006757845,"threshold_uncertainty_score":0.9999894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007645262843477032,"score_gpt":0.1890260590412562,"score_spread":0.1813807961977791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}