{"id":"W2095045485","doi":"10.1271/bbb.100403","title":"Development of a<i>Sleeping Beauty</i>-Based Telomerase Gene Delivery System for Hepatocytes","year":2011,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Telomerase; Telomerase reverse transcriptase; Transgene; Genetic enhancement; Biology; Enhancer; Gene expression; Gene delivery; Gene; Viral vector; Promoter; Cell biology; Molecular biology; Cancer research; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003079973,0.0003617137,0.0003186618,0.0002501438,0.0002322125,0.0003022657,0.0003522554,0.0003382404,0.0005939787],"category_scores_gemma":[0.0001445031,0.0002271304,0.0003246308,0.0001487942,0.0002431362,0.0003141857,0.0002417264,0.000571423,0.0003519981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002325615,"about_ca_system_score_gemma":0.0003309005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004851033,"about_ca_topic_score_gemma":0.0005697808,"domain_scores_codex":[0.999846,0.00002934944,0.00001805527,0.00003234757,0.00005543485,0.00001890224],"domain_scores_gemma":[0.9998996,0.00001512187,0.00003049684,0.00001080843,0.00002010925,0.00002383408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002022458,0.00001225945,0.00004284902,0.00003629578,0.000003126596,0.00003964814,0.00001212536,0.0000602994,0.9971936,0.0002124984,0.00003093757,0.002336123],"study_design_scores_gemma":[0.00001542191,0.000321606,0.0003449792,0.000005073904,0.00002031178,0.000380096,0.000006911065,0.001041581,0.9931727,0.00003555892,0.004648053,0.000007595099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6776979,0.004551136,0.3113021,0.0004838179,0.0003116007,0.0004799428,0.0003173219,0.001046126,0.003810084],"genre_scores_gemma":[0.848833,0.00355326,0.1390764,0.0001368557,0.00007065044,0.0003021071,0.0007804917,0.0001152141,0.007132099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005939787,"threshold_uncertainty_score":0.0019871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03048834710885487,"score_gpt":0.2353622727760892,"score_spread":0.2048739256672343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}