{"id":"W2095045485","doi":"10.1271/bbb.100403","title":"Development of a<i>Sleeping Beauty</i>-Based Telomerase Gene Delivery System for Hepatocytes","year":2011,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Telomerase; Telomerase reverse transcriptase; Transgene; Genetic enhancement; Biology; Enhancer; Gene expression; Gene delivery; Gene; Viral vector; Promoter; Cell biology; Molecular biology; Cancer research; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003013394,0.000206597,0.000330674,0.0001695145,0.0002123964,0.000006374175,0.0002434109,0.0005862189,0.000007627089],"category_scores_gemma":[0.0001277494,0.0001778049,0.00006996076,0.0003315108,0.0008040253,0.00004195605,0.00008067384,0.0001755361,0.000002683745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007486297,"about_ca_system_score_gemma":0.0004156268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001666942,"about_ca_topic_score_gemma":0.000002252489,"domain_scores_codex":[0.9984822,0.000007465742,0.0004238085,0.0005195104,0.0001682811,0.0003987653],"domain_scores_gemma":[0.999163,0.00003378008,0.0001844706,0.0003577865,0.0001121486,0.0001488264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001524679,0.0001254257,0.009156434,0.0005735761,0.00002169381,0.00001412777,0.0001064791,3.303341e-8,0.9797269,0.00009740791,0.00001328086,0.01001224],"study_design_scores_gemma":[0.0006620234,0.0001366129,0.004152919,0.0002371224,0.00003949745,0.00007493234,0.0004367795,0.0001585295,0.9932593,0.000004563808,0.0006315623,0.0002061813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961603,0.0009870901,0.00198422,0.000180918,0.0001133899,0.0003005815,0.00002688046,0.0001800443,0.00006653298],"genre_scores_gemma":[0.9185742,0.0000563976,0.08113265,0.0001238628,0.00002808957,0.00003457006,0.00001501868,0.00001064064,0.00002457801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07914843,"threshold_uncertainty_score":0.7250675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03048834710885487,"score_gpt":0.2353622727760892,"score_spread":0.2048739256672343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}