{"id":"W2095100443","doi":"10.1139/o09-176","title":"Nanopore analysis of the interaction of metal ions with prion proteins and peptidesThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Canadian Food Inspection Agency","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Chemistry; Divalent; Conformational change; Molecule; Biophysics; Metal; Crystallography; Cytosol; Ligand (biochemistry); Peptide; Stereochemistry; Receptor; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187276,0.0002236137,0.0002121494,0.0002207357,0.0002041153,0.0002271852,0.0002090497,0.0003835763,0.0006581875],"category_scores_gemma":[0.0001427364,0.0001129706,0.0002018558,0.0001093231,0.0001381917,0.0002454968,0.0002188357,0.0002985013,0.000186442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001690246,"about_ca_system_score_gemma":0.00007652857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005111139,"about_ca_topic_score_gemma":0.0007122203,"domain_scores_codex":[0.9998773,0.00001223942,0.000007533643,0.00003111313,0.00004586966,0.00002593542],"domain_scores_gemma":[0.9998902,0.00003409753,0.00002151505,0.000008270613,0.00002550608,0.00002029603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001735402,0.000007829601,0.00009992875,0.00001418451,0.000003011366,0.00001683821,0.00000882189,0.00001892978,0.9994211,0.00001386041,0.000009855711,0.0003681822],"study_design_scores_gemma":[0.000002985824,0.0001292811,0.00581494,0.000004285996,0.00001132385,0.0002120075,0.00004400837,0.001469293,0.9913471,0.00003080941,0.0009264551,0.000007499107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840262,0.001265391,0.01306127,0.00005681278,0.000040895,0.00004838142,0.000387477,0.0001269816,0.0009864854],"genre_scores_gemma":[0.9807228,0.000645272,0.01523553,0.0001011406,0.00001196465,0.00006096459,0.000576273,0.00001928191,0.002626769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006581875,"threshold_uncertainty_score":0.002201855,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009175430292538712,"score_gpt":0.2394351462953714,"score_spread":0.2302597160028327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}