{"id":"W2095100443","doi":"10.1139/o09-176","title":"Nanopore analysis of the interaction of metal ions with prion proteins and peptidesThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process.","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Canadian Food Inspection Agency","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Chemistry; Divalent; Conformational change; Molecule; Biophysics; Metal; Crystallography; Cytosol; Ligand (biochemistry); Peptide; Stereochemistry; Receptor; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005573394,0.0001796643,0.0004078351,0.00006480722,0.00009592958,0.00001130615,0.0001544619,0.000259046,0.0003679589],"category_scores_gemma":[0.0003036603,0.0001241869,0.0001314323,0.0003006055,0.0006827706,0.00001453469,0.0001141259,0.0002005751,1.681754e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001139047,"about_ca_system_score_gemma":0.0002736087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006457644,"about_ca_topic_score_gemma":0.000476343,"domain_scores_codex":[0.9987866,0.0001127154,0.0004731231,0.0003182684,0.0001397037,0.0001696227],"domain_scores_gemma":[0.9986317,0.00002822626,0.0006517436,0.0002348472,0.000357056,0.00009646478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001269777,0.00008813984,0.01176406,0.00103919,0.0003499172,1.739479e-7,0.0001889296,0.000003427525,0.9854653,0.00001106601,0.00005452982,0.0009082928],"study_design_scores_gemma":[0.0004136087,0.0001930303,0.0009372118,0.0002670316,0.0005496703,0.000009483253,0.0003557175,0.0000293134,0.9941285,0.00003697258,0.002949502,0.0001300178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883735,0.01033687,0.00001812718,0.0005883213,0.00001751224,0.0003763611,0.0001560293,0.000001500434,0.0001318296],"genre_scores_gemma":[0.995707,0.003626161,0.0003549956,0.00003763454,0.00006121291,0.00001751086,0.0001009245,0.000009481111,0.00008501633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01082685,"threshold_uncertainty_score":0.5064197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009175430292538712,"score_gpt":0.2394351462953714,"score_spread":0.2302597160028327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}