{"id":"W2095101592","doi":"10.2165/00003495-200868010-00005","title":"Pharmacological Treatment of Early Multiple Sclerosis","year":2008,"lang":"en","type":"review","venue":"Drugs","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"EMD Serono; IC Design Education Center; Teva Pharmaceutical Industries; Biogen","keywords":"Medicine; Multiple sclerosis; Pharmacotherapy; Intensive care medicine; Adverse effect; Disease; Fingolimod; Intervention (counseling); Internal medicine; Immunology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009078639,0.0005111351,0.003035934,0.0002651934,0.0001054713,0.000009147907,0.0001910058,0.0002736651,0.0002500854],"category_scores_gemma":[0.0001967854,0.0003173637,0.001227609,0.0003898256,0.000325298,0.00003263788,0.0001236727,0.0002747748,0.0002774665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000429963,"about_ca_system_score_gemma":0.0003160445,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000155352,"about_ca_topic_score_gemma":0.000002259598,"domain_scores_codex":[0.9974822,0.0001908862,0.0007102327,0.0005233454,0.000603164,0.0004902112],"domain_scores_gemma":[0.9981329,0.0007397775,0.0002665581,0.0004392129,0.0001501476,0.0002713622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006459266,0.0008377659,0.0001931139,0.003231116,0.001175853,0.00003823081,0.0003705237,7.215331e-8,0.00003400867,0.000001453119,0.002594514,0.9914588],"study_design_scores_gemma":[0.002212676,0.0009566291,0.001134946,0.004824844,0.001083619,0.00002105163,0.00002286576,0.000005515326,0.00008457592,3.121513e-7,0.9894206,0.0002323607],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001117535,0.994513,0.000001273406,0.00004012872,0.0001322978,0.002186168,0.0001812273,0.00007747136,0.001750841],"genre_scores_gemma":[0.0009256882,0.9965348,0.00031798,0.00001672691,0.0003572413,0.0006434164,0.0001059288,0.00006028755,0.001037964],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9912264,"threshold_uncertainty_score":0.9999278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2802280657794406,"score_gpt":0.4173913160495369,"score_spread":0.1371632502700963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}