{"id":"W2095106279","doi":"10.1139/y01-052","title":"Brain natriuretic peptide appears to act locally as an antifibrotic factor in the heart","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Heart Failure Treatment and Management","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Internal medicine; Brain natriuretic peptide; Atrial natriuretic peptide; Endocrinology; Medicine; Pressure overload; Heart failure; Angiotensin II; Ventricle; Muscle hypertrophy; Fibrosis; Natriuretic peptide; Cardiology; Receptor; Cardiac hypertrophy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001588651,0.0002903139,0.0002418945,0.0002014735,0.0001456419,0.0002478541,0.0002182269,0.0002813042,0.001085173],"category_scores_gemma":[0.0001049279,0.0001111566,0.0001692385,0.00006423986,0.000287999,0.0002756237,0.0001215695,0.0005260402,0.0002641255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000107959,"about_ca_system_score_gemma":0.0001541182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002333275,"about_ca_topic_score_gemma":0.0004543748,"domain_scores_codex":[0.9999115,0.00001485751,0.000006174723,0.00002525439,0.00002525875,0.00001690528],"domain_scores_gemma":[0.9998596,0.00002375386,0.00003047992,0.0000112512,0.00002181777,0.00005303088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001069139,0.0000186194,0.0003191741,0.00005851161,0.000005846908,0.0002039315,0.000009484795,0.00001303381,0.9957967,0.0001136524,0.00004685713,0.00330737],"study_design_scores_gemma":[0.0001193895,0.001990449,0.05698644,0.00004753679,0.00009195443,0.004357157,0.0001104309,0.0006824541,0.9241714,0.0006067601,0.01081477,0.00002118707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9564964,0.02786914,0.009594677,0.0005811329,0.0001960313,0.00005175093,0.0002001766,0.0002097729,0.004801053],"genre_scores_gemma":[0.9822643,0.00717758,0.005905127,0.0003408833,0.0002038014,0.0000621565,0.0003930035,0.00002540257,0.003627846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085173,"threshold_uncertainty_score":0.003630221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978081926486658,"score_gpt":0.312815216123727,"score_spread":0.2930343968588604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}