{"id":"W2095139106","doi":"10.1038/sj.cgt.7700436","title":"Cancer therapy utilizing an adenoviral vector expressing only E1A","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"A549 cell; Viral vector; Genetic enhancement; Cancer research; Adenoviridae; Cell culture; Cisplatin; Apoptosis; Biology; Molecular biology; Chemistry; Gene; Recombinant DNA; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005477286,0.0008832036,0.0006043173,0.0009957402,0.0004611405,0.0008700963,0.0004400113,0.0009854223,0.002045708],"category_scores_gemma":[0.0002840488,0.0003461378,0.0005834272,0.0006590774,0.0005787759,0.0008423966,0.0003318546,0.0010995,0.001009851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007935571,"about_ca_system_score_gemma":0.0008209316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001801951,"about_ca_topic_score_gemma":0.001117874,"domain_scores_codex":[0.9996648,0.00005386833,0.000023709,0.00007991926,0.0000963197,0.0000814152],"domain_scores_gemma":[0.9998902,0.00004256874,0.00001823561,0.00002318277,0.00001177681,0.00001399174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003314514,0.0001895677,0.0002434511,0.0001713242,0.00003986962,0.0001253133,0.00005369963,0.0003148779,0.9791521,0.005738915,0.0007345881,0.01290475],"study_design_scores_gemma":[0.00005933708,0.0002992003,0.000404774,0.0000122023,0.00005116766,0.0003435745,0.00001472652,0.0008071181,0.9826643,0.0003284359,0.01500565,0.000009433462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8066068,0.02463197,0.1144079,0.001638738,0.001477452,0.001671816,0.002804161,0.001785426,0.04497569],"genre_scores_gemma":[0.9244925,0.009422194,0.03344617,0.0002870067,0.00009639546,0.0003901671,0.001995327,0.0001203805,0.02974988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002045708,"threshold_uncertainty_score":0.006843626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07070697776674101,"score_gpt":0.3515561966201444,"score_spread":0.2808492188534034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}