{"id":"W2095139106","doi":"10.1038/sj.cgt.7700436","title":"Cancer therapy utilizing an adenoviral vector expressing only E1A","year":2002,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"A549 cell; Viral vector; Genetic enhancement; Cancer research; Adenoviridae; Cell culture; Cisplatin; Apoptosis; Biology; Molecular biology; Chemistry; Gene; Recombinant DNA; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002398078,0.0004180863,0.0003108282,0.00009943573,0.0002981384,0.0001139262,0.0006779774,0.0002386088,0.002268346],"category_scores_gemma":[0.000007746701,0.0003841271,0.0001764894,0.0002520353,0.0001880806,0.0000252581,0.00006461643,0.0002785359,0.00002774617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063734,"about_ca_system_score_gemma":0.0003002589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002027857,"about_ca_topic_score_gemma":0.000415438,"domain_scores_codex":[0.9974211,0.0002476638,0.0003052645,0.0008354008,0.0004002863,0.0007902557],"domain_scores_gemma":[0.9985065,0.00001305782,0.0001272037,0.0009278376,0.0001670847,0.0002583556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001665605,0.0001376778,0.001183105,0.000004758743,0.0001524997,0.000004764175,0.0003465314,0.0001678646,0.7532352,0.000004436337,0.001593114,0.2415044],"study_design_scores_gemma":[0.002465033,0.002388178,0.001320241,0.00002234,0.000007152688,0.00000845469,0.00006253469,0.000301542,0.9273293,0.00002395282,0.06555135,0.0005199412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8823854,0.1156591,0.00006125774,0.0005020547,0.000384639,0.0004188324,0.00007053365,0.00006575688,0.0004524341],"genre_scores_gemma":[0.9156468,0.07769846,0.0001736992,0.002332985,0.001946951,0.0002950006,0.00005418931,0.0001517385,0.001700195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2409845,"threshold_uncertainty_score":0.9998611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07070697776674101,"score_gpt":0.3515561966201444,"score_spread":0.2808492188534034,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}