{"id":"W2095142835","doi":"10.1001/jama.2009.468","title":"HIV Studies: Progress in Microbicides, Dead End for an Immune-Boosting Strategy","year":2009,"lang":"en","type":"article","venue":"JAMA","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Human immunodeficiency virus (HIV); Microbicides for sexually transmitted diseases; Boosting (machine learning); Dead end; Intensive care medicine; Immune system; Virology; Immunology; Health services; Artificial intelligence; Population; Environmental health","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04781498,0.001480151,0.002142832,0.002282445,0.003714456,0.01085141,0.004025796,0.004048144,0.01423376],"category_scores_gemma":[0.02915551,0.0006345753,0.001429746,0.003961817,0.005283622,0.00337078,0.002764701,0.006952175,0.002378076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.03826978,"about_ca_system_score_gemma":0.1414826,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.6857004,"about_ca_topic_score_gemma":0.8133286,"domain_scores_codex":[0.9854187,0.006502014,0.0007636377,0.0008000306,0.003907411,0.002608205],"domain_scores_gemma":[0.9465777,0.009977569,0.002601188,0.002523849,0.02547798,0.01284166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003443444,0.0005938879,0.009202437,0.004969078,0.0004881105,0.0002949402,0.0009193159,0.0004444678,0.003341663,0.03443587,0.5107967,0.4310702],"study_design_scores_gemma":[0.002087297,0.001890722,0.0205023,0.007675599,0.0006081776,0.0002488846,0.001108638,0.0003448814,0.002182773,0.007680564,0.9555564,0.0001138436],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.007695294,0.5430554,0.001792356,0.4073553,0.01163548,0.0007040691,0.003071125,0.0002666578,0.02442439],"genre_scores_gemma":[0.1275881,0.5802034,0.01533422,0.2234271,0.01781629,0.0009343426,0.003585389,0.0002756656,0.03083553],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.6857004,"threshold_uncertainty_score":0.6323012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04346288787189423,"score_gpt":0.3455751500080795,"score_spread":0.3021122621361853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}