{"id":"W2095183407","doi":"10.1111/j.1742-4658.2009.07148.x","title":"The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin‐IXα reductase and human biliverdin‐IXβ reductase","year":2009,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Science Foundation Ireland","keywords":"Biliverdin reductase; Biliverdin; Chemistry; Bilirubin; Reductase; Stereochemistry; Biochemistry; Heme; Heme oxygenase; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006332855,0.0002225111,0.0002585094,0.00009189528,0.0004812104,0.00007837145,0.0003828065,0.0001288652,0.00002185818],"category_scores_gemma":[0.0002392003,0.0001365763,0.0001959407,0.0001647022,0.000315866,0.00001525562,0.0001129476,0.0002662403,0.000001841183],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001919396,"about_ca_system_score_gemma":0.0001032905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004021442,"about_ca_topic_score_gemma":0.00004835232,"domain_scores_codex":[0.9983712,0.0002154621,0.0005023381,0.0002952102,0.0002841528,0.0003316284],"domain_scores_gemma":[0.9987177,0.00005219621,0.0002611126,0.0005615725,0.0002150624,0.0001923431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001328236,0.0001202372,0.001004816,0.00001232111,0.00007740442,0.00001036115,0.0002227261,0.00005656324,0.9904293,0.0002426619,0.005798679,0.001892046],"study_design_scores_gemma":[0.0005972894,0.001686367,0.008102406,0.00009142847,0.0001004689,0.000213317,0.0005678043,0.00002249807,0.9753452,0.0004940159,0.01251937,0.000259845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971343,0.00130005,0.00003131092,0.001017236,0.00007104489,0.0002711579,0.00004372323,0.00000680021,0.0001243409],"genre_scores_gemma":[0.9982341,0.0003590741,0.000508867,0.0001751363,0.000307385,0.000005005606,0.00001743202,0.00001929134,0.0003737315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01508416,"threshold_uncertainty_score":0.556942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02808539655336585,"score_gpt":0.2822644655233484,"score_spread":0.2541790689699825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}