{"id":"W2095197824","doi":"10.1371/journal.ppat.1004042","title":"Structural and Functional Characterization of a Complex between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 Subunit of TFIIH","year":2014,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Transactivation; Transcription factor II H; Protein subunit; Biology; Heterotetramer; Pleckstrin homology domain; Viral protein; Biochemistry; Transcription factor; Chemistry; Molecular biology; Genetics; Promoter; Gene expression; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002105804,0.00007544171,0.0002572495,0.00004015739,0.00006315963,0.000003773749,0.0000320105,0.00005007607,0.00003847757],"category_scores_gemma":[0.00005099497,0.0000437919,0.00004674217,0.0001201944,0.0003103338,0.00004034461,0.000008708079,0.00006947599,1.460768e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001035779,"about_ca_system_score_gemma":0.00002521883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003589275,"about_ca_topic_score_gemma":0.000007645935,"domain_scores_codex":[0.9993034,0.0001013568,0.0002270186,0.00009131912,0.0001982704,0.00007861495],"domain_scores_gemma":[0.9994363,0.0001195483,0.0002124843,0.0001094178,0.00009690791,0.00002531425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006456359,0.00003683289,0.1261948,0.0001812534,0.0002084954,1.314889e-7,0.002385144,0.000006207272,0.86321,0.001150795,0.000009274406,0.005971508],"study_design_scores_gemma":[0.003686491,0.0002016614,0.9799206,0.00004965306,0.0002842342,0.000001945004,0.0004754338,0.001054525,0.01316664,0.001059055,0.00004430066,0.00005549837],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975973,0.00005260269,0.0008664149,0.0008870679,0.00001730618,0.0003070961,0.0001252527,0.000005750042,0.0001412159],"genre_scores_gemma":[0.999638,0.00004699278,0.00004334712,0.00008795612,0.00004386027,0.000007896117,0.0001126074,0.00000799349,0.00001140154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8537258,"threshold_uncertainty_score":0.1785782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02347415016286054,"score_gpt":0.222922739696128,"score_spread":0.1994485895332675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}