{"id":"W2095197824","doi":"10.1371/journal.ppat.1004042","title":"Structural and Functional Characterization of a Complex between the Acidic Transactivation Domain of EBNA2 and the Tfb1/p62 Subunit of TFIIH","year":2014,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Transactivation; Transcription factor II H; Protein subunit; Biology; Heterotetramer; Pleckstrin homology domain; Viral protein; Biochemistry; Transcription factor; Chemistry; Molecular biology; Genetics; Promoter; Gene expression; Gene; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000180573,0.000326065,0.0002576077,0.0001131407,0.0003116591,0.0001804628,0.0004321492,0.0002785096,0.0009177327],"category_scores_gemma":[0.0004085549,0.0001277072,0.0002152468,0.0001521675,0.0001886673,0.0001811918,0.0001314402,0.0004743993,0.0002256234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581902,"about_ca_system_score_gemma":0.0001858612,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002582415,"about_ca_topic_score_gemma":0.001906268,"domain_scores_codex":[0.9998882,0.00001859057,0.000006016912,0.00002850846,0.00003953361,0.00001923329],"domain_scores_gemma":[0.9998179,0.00003901082,0.00003466714,0.00001217585,0.00003985714,0.00005638448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001984595,0.0000662172,0.0005778306,0.00004906707,0.00002086496,0.0001465706,0.00005795867,0.0004289462,0.9972676,0.0001183016,0.000105796,0.0009623257],"study_design_scores_gemma":[0.00006480231,0.0002640972,0.01561852,0.00001503397,0.00005248141,0.0007878862,0.000179764,0.01334724,0.9635409,0.0001460337,0.005954254,0.00002907135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970899,0.0006158151,0.001390381,0.00009891095,0.00001463477,0.000009892713,0.0002430826,0.00002135229,0.0005161487],"genre_scores_gemma":[0.9952506,0.0003840036,0.001723855,0.00006584328,0.00001378004,0.00001381691,0.001341062,0.00001944751,0.00118756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002582415,"threshold_uncertainty_score":0.005134821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02347415016286054,"score_gpt":0.222922739696128,"score_spread":0.1994485895332675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}