{"id":"W2095209497","doi":"10.1002/prot.21199","title":"NMR structure and binding studies confirm that PA4608 from <i>Pseudomonas aeruginosa</i> is a PilZ domain and a c‐di‐GMP binding protein","year":2006,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; University of Wyoming","keywords":"Guanosine; Biochemistry; Signal transducing adaptor protein; Binding protein; Binding site; Protein structure; Guanosine monophosphate; Chemistry; Binding domain; Biology; Stereochemistry; Nucleotide; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009977118,0.0004166473,0.0003653804,0.0001326991,0.0003515638,0.0001876932,0.0001132052,0.0005730728,0.00002198906],"category_scores_gemma":[0.00002669706,0.0003233855,0.00004988124,0.0001408688,0.0003574464,0.00002828444,0.0002854139,0.0002569092,0.000001325177],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001838188,"about_ca_system_score_gemma":0.00003725256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005487485,"about_ca_topic_score_gemma":0.0001707416,"domain_scores_codex":[0.9985638,0.00003714177,0.0004029963,0.0004409664,0.0001871818,0.0003678702],"domain_scores_gemma":[0.999233,0.0000119079,0.0002855482,0.0002837042,0.00008268213,0.000103177],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001528315,0.0000124579,0.003007244,0.0001676598,0.0001455552,0.0000017852,0.000225251,9.017664e-7,0.9868824,0.0003299421,0.0002855106,0.008788392],"study_design_scores_gemma":[0.002471568,0.0008432321,0.003368133,0.0001380371,0.0001280483,0.0001283061,0.001569108,0.0001621748,0.9575371,0.005370473,0.02745417,0.0008296428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953166,0.00175012,0.0007351205,0.0004782452,0.0002075155,0.0008836958,0.0005233128,0.0000451108,0.00006023379],"genre_scores_gemma":[0.9856164,0.0005009664,0.0128031,0.0002568211,0.000279619,0.00002690948,0.0003655752,0.00002718442,0.0001234677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02934536,"threshold_uncertainty_score":0.9999218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008744382100391447,"score_gpt":0.207684373333078,"score_spread":0.1989399912326865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}