{"id":"W2095209497","doi":"10.1002/prot.21199","title":"NMR structure and binding studies confirm that PA4608 from <i>Pseudomonas aeruginosa</i> is a PilZ domain and a c‐di‐GMP binding protein","year":2006,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; University of Wyoming","keywords":"Guanosine; Biochemistry; Signal transducing adaptor protein; Binding protein; Binding site; Protein structure; Guanosine monophosphate; Chemistry; Binding domain; Biology; Stereochemistry; Nucleotide; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008685995,0.0003162297,0.0002366847,0.00009421559,0.0002391279,0.0001471323,0.0001881258,0.000449801,0.002561956],"category_scores_gemma":[0.0002803823,0.0001010812,0.000272956,0.0001414674,0.0001615754,0.000174152,0.0001390129,0.0005134835,0.001430751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002002321,"about_ca_system_score_gemma":0.0001142752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009449742,"about_ca_topic_score_gemma":0.0008693985,"domain_scores_codex":[0.9999195,0.00001212001,0.000005015055,0.00001801051,0.00002565264,0.000019733],"domain_scores_gemma":[0.9998241,0.00003462193,0.00003585426,0.00001449096,0.0000311039,0.00005987007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008259412,0.00004034501,0.0007991971,0.00003873849,0.000004447597,0.0000803978,0.00002790029,0.0001122154,0.9970312,0.00008677619,0.0001445331,0.001551593],"study_design_scores_gemma":[0.00004156846,0.0005523611,0.02670974,0.00001322757,0.00001886962,0.002829725,0.00009957976,0.003337106,0.9541197,0.0002362759,0.01202061,0.00002130519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905482,0.0005768987,0.003777944,0.0003203177,0.00002137994,0.0000277816,0.0009977103,0.000106891,0.003622904],"genre_scores_gemma":[0.9749215,0.0005518393,0.01451746,0.0003024658,0.00001768574,0.00003117947,0.006429853,0.00005996506,0.003168052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002561956,"threshold_uncertainty_score":0.008570611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008744382100391447,"score_gpt":0.207684373333078,"score_spread":0.1989399912326865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}