{"id":"W2095274433","doi":"10.1021/op060073o","title":"Measurement and Prediction of Solubility of Paracetamol in Water−Isopropanol Solution. Part 1. Measurement and Data Analysis","year":2006,"lang":"en","type":"article","venue":"Organic Process Research & Development","topic":"Crystallization and Solubility Studies","field":"Materials Science","cited_by":108,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Solubility; Gravimetric analysis; Chemistry; Aqueous solution; Chemometrics; Chromatography; Analytical Chemistry (journal); Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00909637,0.0001407632,0.0003828981,0.0002940048,0.0002277039,0.00004763044,0.0003179664,0.00005878689,0.0001502891],"category_scores_gemma":[0.0006248126,0.0001099219,0.00001685604,0.0007158852,0.0003294534,0.000230885,0.0005962136,0.0001092504,0.000003092418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003083635,"about_ca_system_score_gemma":0.0004645953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000318004,"about_ca_topic_score_gemma":0.003585889,"domain_scores_codex":[0.9958066,0.0002565982,0.0007951012,0.0006427393,0.002092679,0.0004062711],"domain_scores_gemma":[0.9979438,0.00003104923,0.0001144003,0.0004837703,0.00135327,0.00007371452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001135817,0.0007170037,0.1231128,0.001070361,0.0001688758,0.000001460531,0.003310531,0.00007063566,0.8695525,0.00004155846,0.0001854798,0.001655199],"study_design_scores_gemma":[0.0006916454,0.00007026667,0.3254231,0.000144661,0.00007108431,0.000001289427,0.0008763045,0.000853496,0.6704947,0.0006197584,0.0005882437,0.0001653581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931839,0.001504007,0.004089141,0.0004088516,0.00003603843,0.0006408176,0.00002901234,0.00002580683,0.00008241647],"genre_scores_gemma":[0.9991857,0.0001750891,0.0005040648,0.000004007748,0.00001110709,0.00005986159,0.00002867302,0.000008161011,0.00002337568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2023103,"threshold_uncertainty_score":0.4482483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.141590186879778,"score_gpt":0.3393274715848786,"score_spread":0.1977372847051007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}