{"id":"W2095317350","doi":"10.1097/01.aids.0000247583.38943.95","title":"Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity","year":2006,"lang":"en","type":"letter","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases","keywords":"Antiretroviral therapy; Replication (statistics); Human immunodeficiency virus (HIV); Medicine; Viral replication; Viral load; Lentivirus; Immunology; Virology; Internal medicine; Viral disease; Oncology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001338841,0.0003044347,0.0004951613,0.0001661398,0.00006849701,0.00001514413,0.0002078917,0.0008676539,0.000960706],"category_scores_gemma":[0.00001750699,0.0002239601,0.0001632878,0.0001413517,0.0003085901,0.00004998233,0.00003641465,0.0008879739,0.001095247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001240941,"about_ca_system_score_gemma":0.00006500623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003278697,"about_ca_topic_score_gemma":0.00001745922,"domain_scores_codex":[0.9982961,0.0002965745,0.000260874,0.0005193974,0.0001169784,0.0005101011],"domain_scores_gemma":[0.9987177,0.00005882945,0.0002493834,0.0008029317,0.0001525583,0.00001860129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0004561904,0.0006281768,0.3168589,0.00004745927,0.001090407,0.0001353127,0.0001167106,1.884776e-7,0.01579044,0.000002481165,0.6644849,0.0003888874],"study_design_scores_gemma":[0.01231449,0.008359103,0.5582328,0.0005142115,0.0004757774,0.00002494336,0.00003900008,3.891991e-7,0.09291335,0.00006445399,0.325782,0.001279529],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856612,0.0005369801,0.00002165868,0.008714166,0.0001109717,0.0005363099,0.002109074,0.00006199936,0.002247648],"genre_scores_gemma":[0.9535617,0.0000353617,0.00005125649,0.01008568,0.0001248608,0.0001091625,0.005843288,0.00005393014,0.0301348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3387029,"threshold_uncertainty_score":0.9999526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02426148579214454,"score_gpt":0.2346884507823933,"score_spread":0.2104269649902488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}