{"id":"W2095328681","doi":"10.1086/505993","title":"Activation of Liver Carnitine Palmitoyltransferase‐1 and Mitochondrial Acetoacetyl‐CoA Thiolase Is Associated with Elevated Ketone Body Levels in the Elasmobranch<i>Squalus acanthias</i>","year":2006,"lang":"en","type":"article","venue":"Physiological and Biochemical Zoology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; National Science Foundation","keywords":"Squalus acanthias; Ketogenesis; Ketone bodies; Thiolase; Carnitine O-palmitoyltransferase; Internal medicine; Spiny dogfish; Carnitine; Carnitine palmitoyltransferase I; Endocrinology; Biology; Beta oxidation; Chemistry; Peroxisome; Metabolism; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007457486,0.0002544981,0.000217018,0.0004605923,0.0002109305,0.0003526186,0.0001626736,0.0002785597,0.0009555471],"category_scores_gemma":[0.000130183,0.0002468652,0.000175487,0.0001466223,0.000437368,0.0001951282,0.0002594661,0.0003058139,0.0001887624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004756445,"about_ca_system_score_gemma":0.0001809097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004684614,"about_ca_topic_score_gemma":0.007780102,"domain_scores_codex":[0.9999149,0.000004432254,0.000008250288,0.00003258419,0.00001687391,0.00002295765],"domain_scores_gemma":[0.9998186,0.000009029812,0.00008095803,0.00001244942,0.00002121768,0.0000577484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004852217,0.00001912902,0.02581429,0.00004075502,0.00002604009,0.0001638329,0.0001317408,0.00001818852,0.9723009,0.00003071979,0.0000324004,0.0009367122],"study_design_scores_gemma":[0.00001820266,0.0004264947,0.9360902,0.000005336425,0.00002732087,0.000655032,0.0003393714,0.0001381094,0.06178168,0.00004446366,0.0004649025,0.000008878113],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995269,0.0001778191,0.00004658535,0.00001394122,0.000002306479,0.000002269398,0.00007372438,0.000005811998,0.0001507697],"genre_scores_gemma":[0.9986778,0.0001505737,0.0001086051,0.00002742984,0.000003838913,0.00001150442,0.0003114741,0.000003080985,0.0007055986],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004684614,"threshold_uncertainty_score":0.009314716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01493614249304179,"score_gpt":0.2239392859240082,"score_spread":0.2090031434309664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}