{"id":"W2095358649","doi":"10.1021/tx500494r","title":"Chemical and Toxicological Characterization of Halobenzoquinones, an Emerging Class of Disinfection Byproducts","year":2015,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Water Treatment and Disinfection","field":"Environmental Science","cited_by":172,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; China Scholarship Council; U.S. Food and Drug Administration; Public Health Agency; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Carcinogen; Oxidative stress; Dichloroacetic acid; DNA damage; Reactive oxygen species; Carcinogenesis; Toxicity; Chemistry; Genotoxicity; Glutathione; Cytotoxicity; Toxicology; Biochemistry; Environmental chemistry; DNA; Biology; In vitro; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007604418,0.00009684374,0.0002106775,0.0001022805,0.00002430105,0.000009281159,0.0001202585,0.0001987739,0.0001259689],"category_scores_gemma":[0.0003682279,0.00008373171,0.00002198913,0.0004387962,0.0005963098,0.0002273858,0.0002326375,0.0002032335,0.00001263776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002404444,"about_ca_system_score_gemma":0.00002520736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001044294,"about_ca_topic_score_gemma":0.00001758889,"domain_scores_codex":[0.9985321,0.0002047646,0.0002717803,0.0003555084,0.0003213873,0.0003145],"domain_scores_gemma":[0.9994462,0.00009339668,0.00006492576,0.0001682412,0.00004403722,0.0001831623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001623938,0.0006000854,0.0766954,0.00001548361,0.00000330996,0.00000375385,0.0001629868,0.000008172401,0.9176941,0.0001908543,0.00003576119,0.004427707],"study_design_scores_gemma":[0.0006527252,0.0004401757,0.07380936,0.00001089094,0.000004708088,0.000008631173,0.00005344846,0.0004182475,0.9227205,0.001615096,0.0001835468,0.00008265543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980977,0.00001239778,0.00001969455,0.0003839729,0.00005913293,0.0002253119,0.000002897511,0.00001505184,0.001183895],"genre_scores_gemma":[0.9996737,0.00001336445,0.0001521242,0.00001327032,0.00003852097,0.00002645877,0.00004172523,0.000007595333,0.00003322719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005026431,"threshold_uncertainty_score":0.341448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1144995385617863,"score_gpt":0.3706656834394451,"score_spread":0.2561661448776588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}