{"id":"W2095397643","doi":"10.1016/j.yjmcc.2006.05.010","title":"PKA-mediated ERK1/2 inactivation and hsp70 gene expression following exercise","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Heart and Stroke Foundation of Canada","keywords":"HSF1; Phosphorylation; Hsp70; Kinase; Protein kinase A; p38 mitogen-activated protein kinases; Chemistry; Protein phosphorylation; Cell biology; Internal medicine; Biology; Endocrinology; Molecular biology; Heat shock protein; Biochemistry; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000264498,0.0005610975,0.0007586899,0.0003137582,0.0003959196,0.0004560754,0.0003744485,0.0005271912,0.004013508],"category_scores_gemma":[0.0003858765,0.0003855581,0.0006338418,0.0002707885,0.0008743165,0.0005563155,0.0004600399,0.001818513,0.0004442626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004726313,"about_ca_system_score_gemma":0.0004303156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001346873,"about_ca_topic_score_gemma":0.002102873,"domain_scores_codex":[0.9997496,0.0000255842,0.00001185262,0.00004901616,0.00003057333,0.0001334138],"domain_scores_gemma":[0.999817,0.00003693685,0.00003461679,0.00002919066,0.00001724058,0.00006507291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01725234,0.0003362176,0.0004216571,0.0001394247,0.00003284402,0.0001557301,0.00009248022,0.0001702384,0.977291,0.0002947251,0.0002305929,0.003582793],"study_design_scores_gemma":[0.0004856539,0.001808213,0.05282647,0.00002893876,0.00006961393,0.0002850686,0.0002758669,0.001690333,0.9409823,0.0003438285,0.001179119,0.00002454757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993592,0.001653397,0.001625508,0.000294741,0.000149794,0.00009117936,0.0007788374,0.00006563008,0.00174902],"genre_scores_gemma":[0.9918207,0.0007378726,0.0007191894,0.000122191,0.00008502629,0.0002369777,0.0006382615,0.00003445133,0.005605336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004013508,"threshold_uncertainty_score":0.01342654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00619396282937409,"score_gpt":0.2314961754189279,"score_spread":0.2253022125895538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}