{"id":"W2095400026","doi":"10.1111/j.1523-1755.2004.00842.x","title":"Evaluation of mutation screening as a first line test for the diagnosis of the primary hyperoxalurias","year":2004,"lang":"en","type":"article","venue":"Kidney International","topic":"Kidney Stones and Urolithiasis Treatments","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Test (biology); Mutation; Medicine; Primary (astronomy); Line (geometry); Genetics; Biology; Gene; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005311605,0.00008957935,0.0001342152,0.00005737715,0.00008117267,0.000008196907,0.0001517806,0.00004563695,0.0001353239],"category_scores_gemma":[0.004914213,0.00005177326,0.0001583822,0.0001115401,0.00006785204,0.00006544733,0.00003830623,0.0000621663,0.000004225457],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001588242,"about_ca_system_score_gemma":0.0004493726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002150417,"about_ca_topic_score_gemma":0.00001110749,"domain_scores_codex":[0.9986012,0.00002268306,0.0002907552,0.000132584,0.0008682897,0.00008451164],"domain_scores_gemma":[0.9983941,0.0003391568,0.0002238433,0.0001990875,0.0007806623,0.00006316057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0011141,0.005175791,0.8098462,0.0003073958,0.004085532,0.000005685019,0.003893118,0.009512275,0.005281444,0.005039453,0.009710928,0.146028],"study_design_scores_gemma":[0.01464145,0.000662197,0.9112113,0.0007496292,0.002262273,0.0000782465,0.0001651405,0.009095805,0.04709876,0.003464825,0.01044555,0.0001248653],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8775069,0.0004617698,0.003803832,0.1087923,0.001097981,0.002614261,0.0006228785,0.00002851614,0.005071594],"genre_scores_gemma":[0.9961279,0.00004926818,0.001544467,0.00147534,0.0001828502,0.0002523164,0.0001607234,0.00001284167,0.0001942835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1459032,"threshold_uncertainty_score":0.5883126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04733717316318703,"score_gpt":0.3308114009728073,"score_spread":0.2834742278096203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}