{"id":"W2095421930","doi":"10.1021/ja904659e","title":"Leaving Group Assistance in the La<sup>3+</sup>-Catalyzed Cleavage of Dimethyl (<i>o</i>-Methoxycarbonyl)aryl Phosphate Triesters in Methanol","year":2009,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chemistry; Aryl; Substituent; Catalysis; Methanol; Medicinal chemistry; Phosphate; Reaction rate constant; Cleavage (geology); Leaving group; Dimethyl carbonate; Stereochemistry; Kinetics; Organic chemistry; Alkyl","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001460451,0.0002468076,0.0006654011,0.00003162437,0.00005526639,0.00004673591,0.001152183,0.0001312932,0.00003266857],"category_scores_gemma":[0.0006025892,0.0001641616,0.0007086514,0.001149353,0.0004845429,0.0001724806,0.0001089495,0.001165903,4.200729e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002516084,"about_ca_system_score_gemma":0.00008579836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003118359,"about_ca_topic_score_gemma":0.000001015526,"domain_scores_codex":[0.9978097,0.0001258984,0.0008921541,0.0002375974,0.0006000003,0.0003346383],"domain_scores_gemma":[0.9972376,0.001006646,0.001165796,0.0004350413,0.00007370111,0.00008118008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001786864,0.0003171659,0.005454917,0.00005535552,0.00007791484,0.00001083838,0.002052323,0.00008429648,0.9856185,0.00002011341,0.0004998102,0.00563013],"study_design_scores_gemma":[0.001317692,0.00002935391,0.006183447,0.0001655828,0.00008917716,0.0000493448,0.003811389,0.0002958188,0.9862481,0.0003953676,0.001182222,0.0002325408],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995873,0.0004390662,0.00008711018,0.002280673,0.00002428237,0.0000598483,0.000008403716,0.00001096119,0.001216688],"genre_scores_gemma":[0.9973447,0.0002161489,0.001559037,0.0006782435,0.0001229577,0.00000345965,0.000002915976,0.00001847774,0.00005406038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005397589,"threshold_uncertainty_score":0.6694317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008986275596600483,"score_gpt":0.2501997173513211,"score_spread":0.2412134417547206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}