{"id":"W2095444837","doi":"10.1002/glia.22298","title":"Comparison of polarization properties of human adult microglia and blood‐derived macrophages","year":2012,"lang":"en","type":"article","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":475,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Killam Trusts; McGill University","keywords":"Microglia; Biology; Phagocytosis; Macrophage; Cell biology; Inflammation; Immunology; CD80; Parenchyma; Neuroinflammation; In vitro; CD40; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006148917,0.00008945397,0.0001561935,0.00006895745,0.00009658273,0.00001689496,0.00008653472,0.00003605495,0.00003375091],"category_scores_gemma":[0.0001336396,0.0000797957,0.00002472042,0.0001044962,0.00009103854,0.000179748,0.00004194839,0.00005889019,0.000007377092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002569502,"about_ca_system_score_gemma":0.000007639163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008079167,"about_ca_topic_score_gemma":0.000002358213,"domain_scores_codex":[0.9991632,0.0001036553,0.0002925615,0.0001445206,0.0001660582,0.0001300008],"domain_scores_gemma":[0.9995346,0.00001603749,0.0001940904,0.0001407308,0.00006306583,0.00005145333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001122916,0.0001023842,0.005806673,0.00005437489,0.000001749107,3.340622e-7,0.0008310162,0.000002439573,0.9872037,0.005857363,0.00002290413,0.0001058394],"study_design_scores_gemma":[0.0002856712,0.00009043189,0.003666144,0.00001629385,0.00001484639,0.000004847191,0.00003929176,0.0001649639,0.9955929,0.00003112492,0.00002161214,0.00007185178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992893,0.0000915174,0.00009743713,0.00005939167,0.0001416961,0.0001596273,0.000007606318,0.00003510696,0.0001182987],"genre_scores_gemma":[0.9993242,0.00001506966,0.0001961684,0.0001265946,0.00003079154,0.000004070835,0.000002000078,0.00001146134,0.0002896258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008389228,"threshold_uncertainty_score":0.3253974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05337472265180488,"score_gpt":0.2935319544547495,"score_spread":0.2401572318029446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}