{"id":"W2095472825","doi":"10.1016/j.cell.2005.08.032","title":"Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte","year":2005,"lang":"en","type":"article","venue":"Cell","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":1445,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences; U.S. Public Health Service","keywords":"Calreticulin; CD47; Phosphatidylserine; Biology; Cell biology; Phagocyte; Efferocytosis; Apoptosis; Cell; Receptor; Transmembrane protein; Phagocytosis; Macrophage; Endoplasmic reticulum; Biochemistry; In vitro; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002858813,0.0004153558,0.0006405389,0.0003558735,0.0003062375,0.0008124711,0.0002662742,0.0006917709,0.001462267],"category_scores_gemma":[0.0003902289,0.000203558,0.0004537671,0.0001494216,0.0003647552,0.0007267856,0.0005228676,0.001567682,0.0009833763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001010735,"about_ca_system_score_gemma":0.0002989638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004257478,"about_ca_topic_score_gemma":0.000777479,"domain_scores_codex":[0.9994392,0.0000988059,0.00003061529,0.00008754936,0.0001466933,0.0001971962],"domain_scores_gemma":[0.9996675,0.00005488591,0.00007050529,0.00004535299,0.00008514267,0.00007666719],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000281659,0.00001762289,0.0002376453,0.00004768583,0.000005611323,0.0001879585,0.00002856756,0.00003876013,0.9965318,0.0003637731,0.0001072758,0.002151724],"study_design_scores_gemma":[0.00002068451,0.0001214944,0.006019758,0.00001311011,0.00001387402,0.00062291,0.0001031369,0.001309618,0.9889765,0.000225912,0.002566881,0.000006021574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736748,0.008400363,0.01246039,0.0006846872,0.0001740017,0.00004616143,0.0002309516,0.000200668,0.004127946],"genre_scores_gemma":[0.9896006,0.001419582,0.003712908,0.0001683086,0.00004643523,0.00002403773,0.0003063764,0.00004570656,0.004675915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001462267,"threshold_uncertainty_score":0.007333398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357994995463818,"score_gpt":0.2391788196968609,"score_spread":0.2155988697422227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}