{"id":"W2095485041","doi":"10.1111/j.2041-1014.2010.00566.x","title":"Synergistic effects of lipopolysaccharides from periodontopathic bacteria on pro-inflammatory cytokine production in an<i>ex vivo</i>whole blood model","year":2010,"lang":"en","type":"article","venue":"Molecular Oral Microbiology","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Treponema denticola; Tannerella forsythia; Porphyromonas gingivalis; Forsythia; Periodontitis; Tumor necrosis factor alpha; Ex vivo; Lipopolysaccharide; Population; Immunology; Cytokine; Microbiology; Chronic periodontitis; Interleukin; Medicine; Biology; In vivo; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004104275,0.0008029906,0.0005487321,0.0002014057,0.0001080138,0.0004003707,0.0001966002,0.000326916,0.0006067135],"category_scores_gemma":[0.0001896532,0.0001783568,0.0004993175,0.0001441688,0.0002458437,0.0002379354,0.0002981022,0.000687973,0.000191062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001114035,"about_ca_system_score_gemma":0.0002263491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000869114,"about_ca_topic_score_gemma":0.0001631246,"domain_scores_codex":[0.999737,0.0001017173,0.00002139759,0.00002972438,0.00004994584,0.00006017486],"domain_scores_gemma":[0.9998145,0.00004772129,0.00005513537,0.00001776977,0.000015799,0.00004904375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00215733,0.0002703482,0.000212202,0.0001247926,0.00001589008,0.00009321589,0.0000221507,0.0001258853,0.9952331,0.00002464159,0.0000252324,0.001695171],"study_design_scores_gemma":[0.0002946444,0.01763169,0.004061842,0.00002976487,0.0001297548,0.0003814851,0.00007875438,0.0009532776,0.9752324,0.00006636074,0.001124703,0.00001540448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960856,0.001784655,0.001505501,0.00006374771,0.00005429445,0.00006391871,0.0001015401,0.00002218497,0.0003184544],"genre_scores_gemma":[0.9919493,0.00207823,0.004790942,0.000114754,0.00005696132,0.0001312094,0.0002991394,0.00001020586,0.0005692682],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008029906,"threshold_uncertainty_score":0.002170563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009759866473807161,"score_gpt":0.2608528972426593,"score_spread":0.2510930307688521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}