{"id":"W2095491985","doi":"10.1016/j.antiviral.2012.08.010","title":"The antiviral activity and mechanism of action of (S)-[3-hydroxy-2-(phosphonomethoxy)propyl] (HPMP) nucleosides","year":2012,"lang":"en","type":"review","venue":"Antiviral Research","topic":"Cytomegalovirus and herpesvirus research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Polymerase; Biology; DNA polymerase; Nucleic acid; Reverse transcriptase; DNA; Virology; RNA; Primer (cosmetics); Virus; Viral replication; Genetics; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001935569,0.000630075,0.0007756341,0.0009127329,0.0001365811,0.0004819689,0.0005765109,0.0004596791,0.001860793],"category_scores_gemma":[0.000173684,0.0002087997,0.0002711657,0.0008131914,0.0002452937,0.0005842004,0.0002837156,0.0006809277,0.0009189695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003078299,"about_ca_system_score_gemma":0.0003514059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006810523,"about_ca_topic_score_gemma":0.001099819,"domain_scores_codex":[0.9999361,0.000008032423,0.000008789258,0.0000134079,0.00002328718,0.0000103728],"domain_scores_gemma":[0.9999421,0.00002261566,0.00001711782,0.000001885725,0.00001084302,0.000005437717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002261066,0.00008423499,0.0001732236,0.01462291,0.00006111237,0.0002892328,0.00006139235,0.000579351,0.03321381,0.002392892,0.005821018,0.9424747],"study_design_scores_gemma":[0.00005785598,0.0004861401,0.001935315,0.002063451,0.0002170399,0.002776217,0.00008330276,0.0002151532,0.02340389,0.001673359,0.9670482,0.0000401426],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009782988,0.9976804,0.0001321146,0.0000538415,0.00004950995,0.000004013744,0.00002091977,0.000005210682,0.001075547],"genre_scores_gemma":[0.004093481,0.9946403,0.0002393698,0.00006192267,0.00006318412,0.000006221186,0.00003596652,0.00000103034,0.0008586342],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001860793,"threshold_uncertainty_score":0.00622499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2695881361853387,"score_gpt":0.486886444217496,"score_spread":0.2172983080321573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}