{"id":"W2095519917","doi":"10.3389/fimmu.2013.00133","title":"Advances in T-Cell Epitope Engineering","year":2013,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Epitope; T cell; Computational biology; Cell biology; Biology; Immunology; Antigen; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001130917,0.0005587288,0.0006087697,0.0004570697,0.0002455977,0.001132367,0.0006977904,0.0009003089,0.00416624],"category_scores_gemma":[0.001199384,0.0003201697,0.0006486925,0.000496176,0.000708151,0.001333102,0.001027795,0.002931228,0.002399074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007139181,"about_ca_system_score_gemma":0.0005005837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002742269,"about_ca_topic_score_gemma":0.0003005032,"domain_scores_codex":[0.999324,0.0001594266,0.00004667381,0.0001702691,0.0002179801,0.00008159899],"domain_scores_gemma":[0.9994851,0.0002082297,0.00007557305,0.00009557091,0.00008031003,0.00005520964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0003318318,0.0004339142,0.0007570611,0.001740731,0.0000867226,0.0002537706,0.0002713869,0.008365997,0.5169281,0.1730624,0.006868303,0.2908998],"study_design_scores_gemma":[0.0001181004,0.0009290721,0.001208292,0.0003512958,0.0001541046,0.001844781,0.0001266174,0.01769792,0.4188641,0.07365808,0.4849687,0.00007903124],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1585224,0.2033509,0.5568354,0.00997296,0.002674697,0.0003348875,0.0007971172,0.001251028,0.06626064],"genre_scores_gemma":[0.6505643,0.1267229,0.194631,0.003873893,0.001097052,0.0003904364,0.000998144,0.0003125719,0.02140965],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00416624,"threshold_uncertainty_score":0.01393747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003045386683917874,"score_gpt":0.1791638510933318,"score_spread":0.1761184644094139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}