{"id":"W2095686849","doi":"10.1007/s12079-015-0281-y","title":"Yin and Yang revisited: CCN3 as an anti-fibrotic therapeutic?","year":2015,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Fibrosis; Medicine; Diabetes mellitus; Cancer research; Diabetic nephropathy; Pathological; Nephropathy; Bioinformatics; Internal medicine; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003196458,0.0006301137,0.001026207,0.0008763904,0.000839154,0.002116744,0.001144152,0.003299241,0.004309369],"category_scores_gemma":[0.002281191,0.000244618,0.0006379438,0.0006949523,0.003194248,0.004111895,0.001324377,0.009789125,0.001300665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001299079,"about_ca_system_score_gemma":0.001317802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001244419,"about_ca_topic_score_gemma":0.003545718,"domain_scores_codex":[0.9993535,0.0002273601,0.00006546854,0.00008533423,0.000191306,0.00007704197],"domain_scores_gemma":[0.9992873,0.0003515443,0.00005558561,0.00004524693,0.000166662,0.00009369312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008990379,0.0001866931,0.0005907307,0.002212915,0.0002089647,0.001027981,0.0004457318,0.0004387417,0.00876971,0.1909188,0.3098439,0.4844568],"study_design_scores_gemma":[0.0002443481,0.0003954163,0.0003855091,0.0006806804,0.00005305891,0.0007505415,0.0002226396,0.0002400493,0.001635196,0.0449124,0.9504331,0.00004706995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.002730935,0.6750264,0.002649388,0.2808508,0.02649985,0.00003886154,0.0001002431,0.0001446467,0.01195898],"genre_scores_gemma":[0.05366385,0.6964008,0.005346493,0.1971087,0.02383094,0.0001800822,0.00011259,0.0001417492,0.02321487],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004309369,"threshold_uncertainty_score":0.01690471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04713133947657337,"score_gpt":0.3313568058435608,"score_spread":0.2842254663669874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}