{"id":"W2095765013","doi":"10.3816/ccc.2002.n.017","title":"Toxicity Analysis of the 5-Day Bolus 5-Fluorouracil/Folinic Acid Regimen for the Treatment of ColorectalCarcinoma from 2 Randomized Controlled Trials: A Concern About Dose","year":2002,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; Occupational Cancer Research Centre","funders":"AstraZeneca; Mayo Clinic","keywords":"Medicine; Folinic acid; Regimen; Fluorouracil; Gastroenterology; Chemotherapy; Leukopenia; Internal medicine; Surgery; Neutropenia; Toxicity; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05269987,0.002271597,0.01016513,0.001290959,0.0007109467,0.002945535,0.001987556,0.003202367,0.003282939],"category_scores_gemma":[0.04699165,0.001082016,0.01780838,0.001700263,0.001773652,0.002137701,0.0008522057,0.005029636,0.0004271161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001613714,"about_ca_system_score_gemma":0.002296025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001292921,"about_ca_topic_score_gemma":0.004012448,"domain_scores_codex":[0.9515715,0.03820807,0.005379917,0.001456689,0.002500646,0.0008831102],"domain_scores_gemma":[0.9633521,0.02287879,0.006813017,0.003678503,0.001975478,0.001302097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.8243644,0.001312293,0.004053194,0.0117944,0.0858396,0.000229438,0.0003222823,0.001948414,0.005110207,0.0007329073,0.002136503,0.06215627],"study_design_scores_gemma":[0.8023794,0.07761136,0.0182973,0.001357607,0.08742607,0.000422129,0.0001588881,0.001439226,0.002061128,0.001736335,0.006974644,0.0001359596],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7185063,0.2125584,0.0245942,0.00601861,0.004330081,0.01886545,0.006161642,0.0006079786,0.008357398],"genre_scores_gemma":[0.9578439,0.0209982,0.007716261,0.003273251,0.001032585,0.00476755,0.002335578,0.0001485696,0.001884165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05269987,"threshold_uncertainty_score":0.2787068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207986057366291,"score_gpt":0.407790952093811,"score_spread":0.286992346357182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}