{"id":"W2095765013","doi":"10.3816/ccc.2002.n.017","title":"Toxicity Analysis of the 5-Day Bolus 5-Fluorouracil/Folinic Acid Regimen for the Treatment of ColorectalCarcinoma from 2 Randomized Controlled Trials: A Concern About Dose","year":2002,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; Occupational Cancer Research Centre","funders":"AstraZeneca; Mayo Clinic","keywords":"Medicine; Folinic acid; Regimen; Fluorouracil; Gastroenterology; Chemotherapy; Leukopenia; Internal medicine; Surgery; Neutropenia; Toxicity; Colorectal cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004441766,0.0005455595,0.0103348,0.0001429744,0.0002774982,0.00002696391,0.0003618994,0.0003150875,0.001492208],"category_scores_gemma":[0.008889657,0.0002321068,0.008735443,0.0008554329,0.001410873,0.0000514567,0.00009194538,0.0002414936,0.000003728316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000452245,"about_ca_system_score_gemma":0.0003241606,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001244573,"about_ca_topic_score_gemma":0.001966024,"domain_scores_codex":[0.9922487,0.002372419,0.00357997,0.000716045,0.0006239844,0.0004588553],"domain_scores_gemma":[0.9579999,0.03806545,0.002452188,0.0007053681,0.0005957811,0.000181242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7950774,0.003038421,0.0465455,0.00004101619,0.09154053,0.000008321102,0.0029469,0.00007542111,0.0006119441,0.00007923441,0.002347952,0.05768735],"study_design_scores_gemma":[0.6856439,0.007091035,0.1726707,0.0001530585,0.1043034,0.000001715548,0.0003886551,0.02065812,0.005499743,0.0001490335,0.0030754,0.0003652844],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9196103,0.06281419,0.00005758882,0.002553268,0.001467518,0.011274,0.0008990215,0.0000398392,0.001284338],"genre_scores_gemma":[0.970311,0.02141985,0.00006890043,0.000413084,0.0006254553,0.005952664,0.0000293179,0.00003582018,0.001143849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1261252,"threshold_uncertainty_score":0.9994589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207986057366291,"score_gpt":0.407790952093811,"score_spread":0.286992346357182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}