{"id":"W2095776124","doi":"10.1093/gbe/evv095","title":"Dual Organellar Targeting of Aminoacyl-tRNA Synthetases in Diatoms and Cryptophytes","year":2015,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research; Dalhousie University","funders":"Canadian Institutes of Health Research; Canadian Institute for Advanced Research","keywords":"Biology; Plastid; Phaeodactylum tricornutum; Cellular compartment; Compartment (ship); Organelle; Aminoacyl tRNA synthetase; Protein targeting; Cytosol; Thalassiosira pseudonana; Mitochondrion; Translation (biology); Protein subcellular localization prediction; Cell biology; Subcellular localization; Cytoplasm; Biochemistry; Endomembrane system; Protein biosynthesis; Gene; Transfer RNA; Chloroplast; Membrane protein; Cell; Algae; RNA; Golgi apparatus; Botany; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001972087,0.00009306056,0.0001425608,0.00003272495,0.00005909396,0.000002554259,0.0000385829,0.0001135585,0.000001428614],"category_scores_gemma":[0.00008758672,0.00008437608,0.00001717457,0.00004371711,0.0001658182,9.05179e-7,0.0001481128,0.00003584596,9.286623e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008254252,"about_ca_system_score_gemma":0.00002852486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005967847,"about_ca_topic_score_gemma":0.00002515307,"domain_scores_codex":[0.9994118,0.00005233254,0.0001548122,0.0002070535,0.00002400475,0.0001500425],"domain_scores_gemma":[0.9997538,0.000014755,0.00005799741,0.00008456725,0.00004293655,0.00004597112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00004153959,0.00001732911,0.2887987,0.00001117571,0.00002365073,5.517096e-7,0.0001637185,0.00002262179,0.7102875,0.0003308203,0.00002354364,0.0002788533],"study_design_scores_gemma":[0.001090945,0.0007913677,0.9363569,0.00001038363,0.00003356767,0.00003224278,0.0008788646,0.00006764546,0.0491322,0.004343308,0.00693268,0.0003298743],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721555,0.02737013,0.0001466957,0.00003808938,0.0000837357,0.00007255848,0.00002884385,0.000001709692,0.0001027304],"genre_scores_gemma":[0.9980561,0.00127886,0.0004654893,0.00002073379,0.000118469,0.000005266711,0.00003668266,0.000005746959,0.0000126818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6611553,"threshold_uncertainty_score":0.3440757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01020453472648226,"score_gpt":0.2239523767185775,"score_spread":0.2137478419920953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}