{"id":"W2095790139","doi":"10.2353/ajpath.2007.070555","title":"Deletion of Integrin-Linked Kinase from Skeletal Muscles of Mice Resembles Muscular Dystrophy Due to α7β1-Integrin Deficiency","year":2007,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; McGill University","funders":"National Institute of Child Health and Human Development; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institutes of Health; Eusko Jaurlaritza; National Institute of Neurological Disorders and Stroke; Directorate for Biological Sciences; Howard Hughes Medical Institute","keywords":"Integrin-linked kinase; Cell biology; ITGA7; Integrin; Focal adhesion; Sarcolemma; Biology; Paxillin; Actin cytoskeleton; PTK2; Dystroglycan; Muscular dystrophy; Signal transduction; Cytoskeleton; Extracellular matrix; Kinase; Myocyte; Protein kinase A; Protein kinase C; Receptor; Mitogen-activated protein kinase kinase; Biochemistry; Laminin; Cyclin-dependent kinase 2; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001327048,0.0001973216,0.000954819,0.0008957909,0.00003272202,0.000005338901,0.0003719835,0.0001093248,0.0001195255],"category_scores_gemma":[0.001230647,0.000158031,0.0003428812,0.0007636765,0.00069395,0.00005018243,0.0001257922,0.0006688566,0.00001765291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001205687,"about_ca_system_score_gemma":0.0002228193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005488122,"about_ca_topic_score_gemma":0.00005436474,"domain_scores_codex":[0.9970856,0.0003537041,0.001125671,0.0002868268,0.000723102,0.0004250587],"domain_scores_gemma":[0.9970589,0.0004447527,0.0008052516,0.0003935304,0.0009535435,0.0003439931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001197504,0.0003832308,0.003938972,0.00004515108,0.00005381631,0.004294993,0.0006542108,0.00003074921,0.8920684,0.00009729592,0.00007129044,0.09716437],"study_design_scores_gemma":[0.003971749,0.02168434,0.4818914,0.0007651579,0.0003136228,0.005374959,0.0126354,0.00009367149,0.4708169,0.0005896949,0.001431343,0.0004317212],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9709963,0.0005124152,0.02732845,0.0004766968,0.0001237535,0.0001976104,0.00001590848,0.000008242906,0.0003406325],"genre_scores_gemma":[0.9710256,0.0001289524,0.02848265,0.0001547031,0.0001429648,0.000002153075,0.000007683167,0.00002948041,0.00002584441],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4779524,"threshold_uncertainty_score":0.6444318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01471812212630359,"score_gpt":0.3093136232726491,"score_spread":0.2945955011463455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}