{"id":"W2095821741","doi":"10.1038/ng.782","title":"A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease","year":2011,"lang":"en","type":"review","venue":"Nature Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":686,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences; McGill Genome Centre; Population Health Research Institute; McMaster University; McGill University","funders":"British Heart Foundation; National Institute for Health and Care Research","keywords":"Biology; Locus (genetics); Genome-wide association study; Single-nucleotide polymorphism; Genetics; Genetic association; Coronary artery disease; Expression quantitative trait loci; SNP; Quantitative trait locus; Heritability; Gene; Genotype; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002023864,0.00133278,0.002153393,0.001552939,0.0002530157,0.001087716,0.001392326,0.001851621,0.001538038],"category_scores_gemma":[0.002083444,0.0003853848,0.0005614571,0.002269217,0.0008602573,0.001045375,0.0008464911,0.002310742,0.001224678],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006221211,"about_ca_system_score_gemma":0.001556605,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002287077,"about_ca_topic_score_gemma":0.004970618,"domain_scores_codex":[0.9995607,0.00007694904,0.00006166917,0.0001091608,0.0001593681,0.00003224146],"domain_scores_gemma":[0.9984227,0.0008948381,0.0001503305,0.00004696609,0.0003723775,0.0001126654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0001954484,0.00005664373,0.001936366,0.00510859,0.0003111193,0.0003067822,0.00003479335,0.0002036088,0.001281789,0.002142851,0.0310996,0.9573225],"study_design_scores_gemma":[0.0001764472,0.0001624536,0.01430669,0.004922482,0.0009789777,0.003362588,0.0001397363,0.0002022454,0.001103493,0.00768773,0.9668677,0.00008937858],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002256668,0.9972106,0.0005442229,0.001133207,0.0002806535,0.000004153596,0.00004537318,0.0000116637,0.0005445064],"genre_scores_gemma":[0.001057551,0.9968267,0.0006135021,0.0006439541,0.0003537945,0.000007455856,0.00006836912,0.000002113405,0.0004264968],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002287077,"threshold_uncertainty_score":0.01070333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02344848061697748,"score_gpt":0.2966453460297067,"score_spread":0.2731968654127292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}