{"id":"W2095913486","doi":"10.3324/haematol.2010.025338","title":"Prognostic factors identified three risk groups in the LRF CLL4 trial, independent of treatment allocation","year":2010,"lang":"en","type":"article","venue":"Haematologica","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Cancer Research Institute; Cancer Research Institute","keywords":"IGHV@; Internal medicine; Randomization; Oncology; Randomized controlled trial; Medicine; Beta-2 microglobulin; Chronic lymphocytic leukemia; Relative risk; Progression-free survival; Overall survival; Leukemia; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00547157,0.0008225149,0.001917575,0.0004836787,0.000321253,0.001139517,0.0006144503,0.00156994,0.002517473],"category_scores_gemma":[0.005345319,0.0002567471,0.001777349,0.0003753252,0.000631789,0.001046587,0.0007819788,0.001892663,0.0002122396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007883647,"about_ca_system_score_gemma":0.00122568,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000532811,"about_ca_topic_score_gemma":0.001055442,"domain_scores_codex":[0.9967049,0.002371158,0.0001334456,0.0002482425,0.0001986417,0.0003436479],"domain_scores_gemma":[0.9973092,0.001240225,0.0007038369,0.0001972709,0.00009836991,0.0004511559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8963606,0.001233502,0.05240505,0.0003509092,0.001653291,0.00008160847,0.0001092807,0.00178602,0.001546445,0.0002318176,0.001355,0.04288651],"study_design_scores_gemma":[0.6813651,0.1132953,0.1808591,0.0004349478,0.006301374,0.0004066911,0.000212556,0.00751626,0.001609288,0.003542589,0.004322766,0.0001340726],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928289,0.003878774,0.0005421889,0.0007296902,0.0000644124,0.0003634696,0.0004177896,0.00003489886,0.001139919],"genre_scores_gemma":[0.99647,0.0003388415,0.0007379847,0.0004822753,0.0001143119,0.0006963168,0.0006679912,0.000007259756,0.0004851205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00547157,"threshold_uncertainty_score":0.0289368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05414269921170813,"score_gpt":0.3289752179945787,"score_spread":0.2748325187828706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}