{"id":"W2095928029","doi":"10.1093/gbe/evu097","title":"Repeated Evolution of Chimeric Fusion Genes in the β-Globin Gene Family of Laurasiatherian Mammals","year":2014,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Biology; Gene; Genetics; Chimeric gene; Gene cluster; Gene duplication; Gene conversion; Gene family; Fusion gene; Globin; Mutant; Pseudogene; Coding region; Recombination; Genome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001927034,0.0001378505,0.0001617881,0.000469332,0.0002726026,0.0002854896,0.0001849968,0.0003173977,0.0003878881],"category_scores_gemma":[0.00023963,0.0001248862,0.0002816866,0.0002600151,0.0003199299,0.0001626559,0.0003746577,0.0003569843,0.0001557743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002948542,"about_ca_system_score_gemma":0.0001260656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003632064,"about_ca_topic_score_gemma":0.0004304014,"domain_scores_codex":[0.9998924,0.0000132351,0.000007970842,0.00004424719,0.00002346209,0.00001871159],"domain_scores_gemma":[0.9998568,0.00003557294,0.0000492554,0.00002215707,0.0000137464,0.00002243729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00005824307,0.000006832145,0.00439765,0.00001676575,0.00001008409,0.0003969331,0.000170054,0.0001091114,0.9899887,0.0003472924,0.00001336032,0.004485051],"study_design_scores_gemma":[0.00003577225,0.0005870627,0.3490364,0.00003819983,0.0001513938,0.01569408,0.0006097202,0.004466181,0.6111539,0.0009237934,0.0172608,0.00004273891],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974648,0.0003531776,0.001586821,0.00002015544,0.000003579693,0.000007095076,0.00004302202,0.0000221522,0.0004991277],"genre_scores_gemma":[0.9960622,0.0003031568,0.002711478,0.00002675827,0.000005933048,0.00000876092,0.0002978358,0.0000110174,0.0005727969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000469332,"threshold_uncertainty_score":0.00213927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007071378985531092,"score_gpt":0.2267420865823405,"score_spread":0.2196707075968094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}