{"id":"W2095937258","doi":"10.1002/hep.26023","title":"Adoptive transfer of ex vivo expanded regulatory T cells in an autoimmune hepatitis murine model restores peripheral tolerance","year":2012,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":105,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Autoimmune hepatitis; Peripheral tolerance; Immunology; Adoptive cell transfer; Central tolerance; Medicine; T cell; Immune tolerance; Regulatory T cell; CXCR3; Ex vivo; Hepatitis; Biology; IL-2 receptor; In vivo; Antigen; Immune system; Chemokine receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001377443,0.0001775074,0.0005386286,0.0001076886,0.00003943831,0.00000306341,0.0001172056,0.0001593074,0.0004386893],"category_scores_gemma":[0.00001238047,0.0001670018,0.0001095683,0.0001196912,0.0002110161,0.0002398693,0.00003484111,0.0002116387,0.000006332173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009495988,"about_ca_system_score_gemma":0.0001394052,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088544,"about_ca_topic_score_gemma":0.0001914122,"domain_scores_codex":[0.9986993,0.0001557921,0.0003728503,0.0002054486,0.0001565781,0.0004100529],"domain_scores_gemma":[0.9991917,0.00003008702,0.00005008943,0.0004726143,0.00009056713,0.0001649146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008964352,0.0009413661,0.9406209,0.0001387502,0.0000411143,0.0000273721,0.003703937,0.0001322233,0.05180668,0.0009405955,0.0001954554,0.0005551455],"study_design_scores_gemma":[0.002544997,0.0004581672,0.9372619,0.00009034111,0.00008475799,0.00003620737,0.0002314531,0.0338511,0.0248203,0.00007258757,0.000331373,0.0002168082],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968673,0.001656264,0.0002547315,0.00008284763,0.0002044889,0.0002846168,0.00003821422,0.00003981265,0.0005717233],"genre_scores_gemma":[0.9982429,0.0003377837,0.0006495839,0.0002956305,0.00005981735,0.00002702779,0.0000257499,0.0000264993,0.0003350684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03371888,"threshold_uncertainty_score":0.6810134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02483018486478749,"score_gpt":0.2714890136638839,"score_spread":0.2466588287990964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}