{"id":"W2096072959","doi":"10.4161/cc.25842","title":"Carbonic anhydrase 9 (CA9) and redox signaling in cancer-associated fibroblasts: Therapeutic implications","year":2013,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; Carbonic anhydrase; Epithelial–mesenchymal transition; Cancer; Cancer research; Enzyme; Cancer cell; Cell biology; Biochemistry; Genetics; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004536698,0.0004712236,0.0005083779,0.0002158302,0.0007327648,0.000928864,0.0004160713,0.007793944,0.004262805],"category_scores_gemma":[0.001563929,0.0002337938,0.0005490344,0.0001839161,0.000818277,0.0005571013,0.0002174609,0.006142303,0.001747757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00154156,"about_ca_system_score_gemma":0.000382681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005458414,"about_ca_topic_score_gemma":0.001040704,"domain_scores_codex":[0.9997312,0.00005718918,0.00002831053,0.00002900864,0.0001087952,0.00004538893],"domain_scores_gemma":[0.999531,0.0002793542,0.00004677412,0.0000199995,0.00004892251,0.0000737901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001456862,0.0004675117,0.001643893,0.0004674727,0.00005976036,0.04007104,0.0001402045,0.0005787651,0.04367572,0.01687266,0.803539,0.09102701],"study_design_scores_gemma":[0.001152139,0.0008977386,0.003486818,0.000223758,0.0001303559,0.03898193,0.0001965496,0.003870853,0.04086631,0.01474444,0.8953844,0.0000648385],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01787546,0.01582067,0.00164007,0.9139006,0.03229784,0.00007728616,0.0001590008,0.0002116525,0.01801732],"genre_scores_gemma":[0.3129722,0.04862977,0.004347717,0.3966548,0.1412843,0.0003736405,0.0002274939,0.000106492,0.09540357],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.007793944,"threshold_uncertainty_score":0.01426053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068407525009392,"score_gpt":0.2330629240079622,"score_spread":0.2223788487578683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}