{"id":"W2096072959","doi":"10.4161/cc.25842","title":"Carbonic anhydrase 9 (CA9) and redox signaling in cancer-associated fibroblasts: Therapeutic implications","year":2013,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Enzyme function and inhibition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Biology; Carbonic anhydrase; Epithelial–mesenchymal transition; Cancer; Cancer research; Enzyme; Cancer cell; Cell biology; Biochemistry; Genetics; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006281486,0.0001890454,0.0001601199,0.00006487309,0.0000638385,0.00003561343,0.00009508414,0.0005775849,0.0001058516],"category_scores_gemma":[0.00001274755,0.0001960372,0.00006245759,0.00009308022,0.00004976385,0.000004700119,0.00004560147,0.0004054937,0.00001234348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006336401,"about_ca_system_score_gemma":0.00007257946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003817987,"about_ca_topic_score_gemma":0.0001697204,"domain_scores_codex":[0.998996,0.0000718177,0.0002036618,0.0003941497,0.00007500897,0.0002593491],"domain_scores_gemma":[0.9995004,0.00001727859,0.0001249049,0.0002604506,0.00005564634,0.00004134561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006127936,0.00003877711,0.0003301949,0.0000466854,0.00002544708,0.00000259213,0.00002864719,0.00007401485,0.5766855,0.000002366296,0.4223866,0.0003730914],"study_design_scores_gemma":[0.001654935,0.0004133869,0.002282252,0.0002476494,0.0001118593,0.00001004454,0.00005857766,0.0004322545,0.2901088,0.0005607214,0.7030619,0.001057648],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9041334,0.006733333,0.00008186128,0.08195835,0.0003685377,0.0007108609,0.0001694604,0.00006002065,0.005784124],"genre_scores_gemma":[0.8506415,0.0009430404,0.00004256436,0.1398051,0.001047854,0.0002150287,0.001778123,0.00007348158,0.005453242],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2865767,"threshold_uncertainty_score":0.7994167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068407525009392,"score_gpt":0.2330629240079622,"score_spread":0.2223788487578683,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}