{"id":"W2096143852","doi":"10.1128/iai.68.3.1156-1163.2000","title":"Synthetic Peptide Immunogens Elicit Polyclonal and Monoclonal Antibodies Specific for Linear Epitopes in the D Motifs of <i>Staphylococcus aureus</i> Fibronectin-Binding Protein, Which Are Composed of Amino Acids That Are Essential for Fibronectin Binding","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; North York General Hospital","funders":"Medical Research Council; Medical Research Council Canada; Health Sciences Centre Foundation","keywords":"Immunogen; Polyclonal antibodies; Epitope; Biology; Monoclonal antibody; Antibody; Molecular biology; Staphylococcus aureus; Peptide; Binding site; Epitope mapping; Biochemistry; Bacteria; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005474362,0.00106022,0.0003849304,0.0004369956,0.0001412235,0.0003412558,0.0004580441,0.0007940998,0.001322216],"category_scores_gemma":[0.0002669483,0.0003039565,0.0004405271,0.0003469346,0.0003096301,0.0002814794,0.0003810292,0.001133152,0.0006702358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005338343,"about_ca_system_score_gemma":0.0002139312,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001717875,"about_ca_topic_score_gemma":0.0002915173,"domain_scores_codex":[0.9994685,0.00009799555,0.00004674493,0.000116829,0.0001331084,0.0001369174],"domain_scores_gemma":[0.9996415,0.0001233206,0.00008298438,0.00002842643,0.00004317804,0.00008060406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008689055,0.0001331803,0.00008746811,0.00005898774,0.000004463369,0.00002802622,0.000008895817,0.00006669955,0.9985384,0.0000988641,0.00004656539,0.0008416032],"study_design_scores_gemma":[0.0001002869,0.001326527,0.002064783,0.00001628103,0.00003388459,0.0003415401,0.00001967177,0.0008019349,0.9926635,0.0000904784,0.00253324,0.000007986903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984225,0.002151359,0.009871629,0.0001317635,0.000141529,0.0003568011,0.0005392914,0.0001020432,0.002480562],"genre_scores_gemma":[0.9783651,0.001731454,0.01437117,0.0003566023,0.0001380857,0.0004578133,0.00188456,0.00004101288,0.002654215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001322216,"threshold_uncertainty_score":0.004423261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02435199473186756,"score_gpt":0.2745855209009538,"score_spread":0.2502335261690863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}