{"id":"W2096148604","doi":"10.1006/abbi.2001.2298","title":"Characterization of Mutants of βHistidine91, βAspartate213, and βAsparagine222, Possible Components of the Energy Transduction Pathway of the Proton-Translocating Pyridine Nucleotide Transhydrogenase of Escherichia coli","year":2001,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council","keywords":"Mutant; Biochemistry; Escherichia coli; Mutagenesis; Enzyme; Site-directed mutagenesis; Chemistry; Binding site; Stereochemistry; Active site; Nucleotide; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000629795,0.0001372094,0.0002783015,0.00001911383,0.00004282461,0.000002020887,0.0002018989,0.00006738147,0.000002417801],"category_scores_gemma":[0.00001897074,0.00009870062,0.0001336852,0.0001865247,0.0008162541,0.000007505702,0.00005876186,0.00006095304,8.415062e-9],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001552825,"about_ca_system_score_gemma":0.00006882205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008344593,"about_ca_topic_score_gemma":0.000003020774,"domain_scores_codex":[0.999029,0.00005960098,0.0004276449,0.0001908453,0.000168302,0.0001246201],"domain_scores_gemma":[0.9991643,0.0000263384,0.0004020995,0.0002857676,0.00008185048,0.00003959267],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003846104,0.0003361761,0.003142663,0.0009910199,0.00009191767,2.391323e-7,0.0002048564,0.00003644757,0.9929875,0.00004203741,3.437915e-7,0.001782176],"study_design_scores_gemma":[0.0005220923,0.0001871875,0.006439241,0.0002697885,0.00004135953,0.000002216546,0.0000783884,0.000475333,0.9918153,0.00006673324,0.0000180206,0.00008437484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988128,0.0002134725,0.0003010678,0.00003961672,0.00001559807,0.0002185533,0.0003301124,0.000001564864,0.00006723184],"genre_scores_gemma":[0.9991162,0.0006114371,0.0001099084,0.000004067553,0.00002493622,0.000007682203,0.00008809064,0.0000114234,0.00002624512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003296578,"threshold_uncertainty_score":0.4024895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009309597522959446,"score_gpt":0.2184740975502886,"score_spread":0.2091645000273292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}