{"id":"W2096148604","doi":"10.1006/abbi.2001.2298","title":"Characterization of Mutants of βHistidine91, βAspartate213, and βAsparagine222, Possible Components of the Energy Transduction Pathway of the Proton-Translocating Pyridine Nucleotide Transhydrogenase of Escherichia coli","year":2001,"lang":"en","type":"article","venue":"Archives of Biochemistry and Biophysics","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council","keywords":"Mutant; Biochemistry; Escherichia coli; Mutagenesis; Enzyme; Site-directed mutagenesis; Chemistry; Binding site; Stereochemistry; Active site; Nucleotide; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001785881,0.0009026225,0.0003838979,0.0002261783,0.0002283954,0.000478481,0.0004093662,0.0004960608,0.0008669619],"category_scores_gemma":[0.000423533,0.0002556854,0.0004175169,0.000318298,0.0002861518,0.0002746246,0.0003152932,0.0006418378,0.0005829181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003224955,"about_ca_system_score_gemma":0.0002274852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001417067,"about_ca_topic_score_gemma":0.000811837,"domain_scores_codex":[0.9998344,0.00003088452,0.00003071515,0.00002939931,0.00004865113,0.00002592914],"domain_scores_gemma":[0.9995814,0.000101693,0.0001277175,0.00005949603,0.00004969823,0.00007995681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001715985,0.00005148982,0.0001884469,0.00002241137,0.000007546613,0.0001292262,0.00002039594,0.0000955127,0.9985344,0.00006405024,0.00001892775,0.000696039],"study_design_scores_gemma":[0.00004470339,0.0002286343,0.004129098,0.000007146052,0.00003660117,0.001079487,0.00006444186,0.0009077362,0.992092,0.00005589054,0.001340723,0.0000136055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959616,0.0003902868,0.002214138,0.0000870916,0.00002422902,0.00003174695,0.0006767933,0.00005174968,0.0005624513],"genre_scores_gemma":[0.9926519,0.0003456276,0.002759978,0.00007099332,0.00001127579,0.00003664621,0.002349554,0.00009411502,0.001680003],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417067,"threshold_uncertainty_score":0.002900243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009309597522959446,"score_gpt":0.2184740975502886,"score_spread":0.2091645000273292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}