{"id":"W2096184369","doi":"10.1261/rna.033209.112","title":"A cellular response linking eIF4AI activity to eIF4AII transcription","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; EIF4E; EIF4G; eIF4A; Initiation factor; EIF4EBP1; Cell biology; Eukaryotic translation; EIF4A1; Heterotrimeric G protein; Eukaryotic initiation factor; Messenger RNA; Protein biosynthesis; Transcription (linguistics); Translation (biology); Molecular biology; Genetics; Signal transduction; Gene; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006257299,0.0001213112,0.0001012124,0.00004019937,0.00008235545,0.00001799515,0.0001252659,0.0001475883,0.00005262345],"category_scores_gemma":[0.00006690154,0.0001188263,0.00008646105,0.00006774299,0.00001272356,0.000007109419,0.00003775855,0.00006096026,0.0001090124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001581153,"about_ca_system_score_gemma":0.0000244685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009098258,"about_ca_topic_score_gemma":0.000002239398,"domain_scores_codex":[0.999096,0.0001827419,0.00009907763,0.000202561,0.0001206119,0.0002990587],"domain_scores_gemma":[0.9994872,0.00001120521,0.00003550062,0.0002928826,0.00002419093,0.0001490134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006337919,0.00004897148,0.00007624498,0.000008841941,0.00001456622,0.000001162897,0.0001540758,0.000003697094,0.9794623,0.00005093822,0.0001569816,0.01938849],"study_design_scores_gemma":[0.0001159958,0.0001588277,0.001125901,0.00001532087,0.000009281456,0.000003518676,0.00002207155,0.000004281733,0.9257809,0.00003824248,0.07257514,0.0001505088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9649111,0.0004695774,0.03313648,0.0002850132,0.0002835708,0.0001907505,0.000005670458,0.00001957063,0.0006982514],"genre_scores_gemma":[0.9962419,0.00002224327,0.001775892,0.0002990888,0.0004440019,0.00003463514,0.000008668662,0.00002322693,0.001150334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07241815,"threshold_uncertainty_score":0.4845595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01787481835940371,"score_gpt":0.2494047138286679,"score_spread":0.2315298954692642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}