{"id":"W2096184369","doi":"10.1261/rna.033209.112","title":"A cellular response linking eIF4AI activity to eIF4AII transcription","year":2012,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; EIF4E; EIF4G; eIF4A; Initiation factor; EIF4EBP1; Cell biology; Eukaryotic translation; EIF4A1; Heterotrimeric G protein; Eukaryotic initiation factor; Messenger RNA; Protein biosynthesis; Transcription (linguistics); Translation (biology); Molecular biology; Genetics; Signal transduction; Gene; G protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002230883,0.0004758895,0.000324327,0.0002441101,0.0001899324,0.0003917589,0.0002010224,0.0003887587,0.001393936],"category_scores_gemma":[0.0002358417,0.0002214365,0.0002945957,0.0001784344,0.000413471,0.000212864,0.0004002561,0.0006904809,0.000393883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004052453,"about_ca_system_score_gemma":0.0002384055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002308267,"about_ca_topic_score_gemma":0.0002719018,"domain_scores_codex":[0.9997773,0.00003778702,0.00001981649,0.00005584161,0.00006204205,0.00004719641],"domain_scores_gemma":[0.9998368,0.00004117825,0.00004854109,0.00001989606,0.0000220281,0.00003147758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009034311,0.00001050081,0.0001266094,0.00002556238,0.000002547789,0.00002188145,0.000004893049,0.00003430435,0.9990637,0.0000821971,0.00001617429,0.000521292],"study_design_scores_gemma":[0.00001329596,0.0002066009,0.004744328,0.00000439593,0.000007944674,0.00008845693,0.00001969475,0.0003818383,0.9929504,0.0001028589,0.001476177,0.000004016968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9788367,0.004582682,0.01058683,0.0003543781,0.0001264842,0.00007794935,0.0006932956,0.0003016962,0.004440078],"genre_scores_gemma":[0.991222,0.001181285,0.00444235,0.0001549329,0.00003809747,0.00007154423,0.0006590002,0.00002586536,0.002204945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001393936,"threshold_uncertainty_score":0.004663229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01787481835940371,"score_gpt":0.2494047138286679,"score_spread":0.2315298954692642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}