{"id":"W2096275987","doi":"10.1074/jbc.m002595200","title":"Structure of a Conserved Domain Common to the Transcription Factors TFIIS, Elongin A, and CRSP70","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Transcription factor; Domain (mathematical analysis); Transcription (linguistics); Computational biology; Biology; Genetics; Evolutionary biology; Gene; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001553678,0.0001290017,0.0002037264,0.000008500145,0.00004284293,0.00001265321,0.0002462312,0.0001937738,0.0002804601],"category_scores_gemma":[0.00008903946,0.00007460926,0.000126129,0.00005119077,0.0001412322,0.000002388749,0.00002678304,0.0001553759,5.185753e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009638053,"about_ca_system_score_gemma":0.00003548534,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003362547,"about_ca_topic_score_gemma":0.000001808401,"domain_scores_codex":[0.9992259,0.00006755085,0.0003127363,0.0001440744,0.0001166827,0.0001330544],"domain_scores_gemma":[0.9994639,0.00003158256,0.0001413069,0.0001688952,0.00006639965,0.0001279415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003526127,0.00004315513,0.01038759,0.00001770635,0.00004118956,0.000005137733,0.0000574689,0.00005008423,0.9880748,0.000002757482,0.0003687229,0.0005987621],"study_design_scores_gemma":[0.000395269,0.0002557325,0.01237362,0.00002303043,0.00002028849,0.00007369155,0.0001238515,0.000001528621,0.9825671,0.0002788719,0.003788199,0.00009882704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982774,0.001101945,0.00005845339,0.0002962097,0.00003801938,0.00006685536,0.00008575225,0.000003213332,0.0000721003],"genre_scores_gemma":[0.9992458,0.00007762888,0.000253327,0.0001963264,0.0001530454,8.779708e-7,0.00002678158,0.000006482882,0.00003978944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005507723,"threshold_uncertainty_score":0.3070842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01514560657906828,"score_gpt":0.2417873499007722,"score_spread":0.226641743321704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}