{"id":"W2096283970","doi":"10.1016/j.cancergencyto.2008.07.006","title":"Methylation status of MGMT gene promoter in meningiomas","year":2008,"lang":"en","type":"article","venue":"Cancer Genetics and Cytogenetics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Cancer Foundation; University of Calgary","funders":"","keywords":"Temozolomide; Methylation; Meningioma; Biology; Cancer research; DNA methylation; Methyltransferase; Gene; Oncology; Radiation therapy; Promoter; Internal medicine; Glioblastoma; Pathology; Medicine; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004153169,0.0001305382,0.0002524998,0.00009553516,0.00004049978,0.000005683145,0.00003133124,0.00007690537,0.00003305152],"category_scores_gemma":[0.000009360535,0.0001156386,0.00004571794,0.0001752028,0.00008268963,0.00001039862,0.00003189811,0.00005263897,0.000001102801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006157444,"about_ca_system_score_gemma":0.0001256778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001851318,"about_ca_topic_score_gemma":0.00009521704,"domain_scores_codex":[0.9990684,0.00001780362,0.00026548,0.0002117003,0.0001810429,0.0002555676],"domain_scores_gemma":[0.9994829,0.00001686961,0.00007544802,0.0001862631,0.00009308908,0.0001454446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004948194,0.0001858406,0.8936709,0.00005096029,0.00007520772,0.00006431514,0.0005760036,0.0003301747,0.08322839,0.00001445147,0.00008792822,0.02166637],"study_design_scores_gemma":[0.001643655,0.0003171083,0.5354686,0.00003990984,0.00009406201,0.00003795342,0.00002470624,0.0006045708,0.4590204,0.00007251003,0.002576736,0.00009977665],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719036,0.02728719,0.00007231846,0.0001159322,0.00006472068,0.0002915479,0.00002777219,0.000007079796,0.0002298663],"genre_scores_gemma":[0.9613701,0.03496848,0.003416394,0.00005491058,0.00005299399,0.00004455279,0.00001635984,0.00002001051,0.00005624385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.375792,"threshold_uncertainty_score":0.4715607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0449501751891623,"score_gpt":0.3071874652584655,"score_spread":0.2622372900693032,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}