{"id":"W2096301773","doi":"10.1021/jm101594s","title":"Selective Depletion of Neuropathy-Related Antibodies from Human Serum by Monolithic Affinity Columns Containing Ganglioside Mimics","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Peripheral Neuropathies and Disorders","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"","keywords":"Ganglioside; Chemistry; Antibody; Monoclonal antibody; Chromatography; Molecular biology; Biochemistry; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527729,0.0004479903,0.0002252455,0.0002414714,0.0001310607,0.0001953582,0.0003107974,0.0002596734,0.0007717906],"category_scores_gemma":[0.0001833376,0.0002129241,0.0001659541,0.0001397834,0.0001074083,0.00009279379,0.0001998011,0.0003158913,0.0004488738],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002232113,"about_ca_system_score_gemma":0.0002528469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00122818,"about_ca_topic_score_gemma":0.002895818,"domain_scores_codex":[0.9998537,0.00002044735,0.000008791384,0.00002976408,0.00004597854,0.0000412416],"domain_scores_gemma":[0.9999197,0.00002033766,0.00001106323,0.000006608058,0.00001970778,0.00002266512],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004807081,0.00001975703,0.0002160677,0.00001929222,0.000008013087,0.00002443048,0.000006129531,0.00002263615,0.9977325,0.0000187758,0.00007788382,0.001806442],"study_design_scores_gemma":[0.00004215079,0.0003946758,0.009103091,0.00001656893,0.00006194777,0.0004353129,0.0000174948,0.001732333,0.984392,0.00003235634,0.003762738,0.000009292694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9586589,0.005156186,0.0315716,0.0001890647,0.00006681064,0.0003465381,0.0005640178,0.0004761236,0.002970763],"genre_scores_gemma":[0.9597755,0.002136147,0.03150317,0.0004384132,0.00005004318,0.0001920132,0.00162768,0.00004656474,0.004230556],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00122818,"threshold_uncertainty_score":0.002581894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01850669403066443,"score_gpt":0.2472690416617757,"score_spread":0.2287623476311113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}