{"id":"W2096337669","doi":"10.1073/pnas.1204935109","title":"Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Medical Research Council; Compute Canada","keywords":"ATP synthase; Cryo-electron microscopy; Protein subunit; ATP synthase gamma subunit; Biophysics; Inner mitochondrial membrane; Crystallography; Mitochondrion; Chemistry; Biology; ATP hydrolysis; Biochemistry; Enzyme; ATPase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001295846,0.0001679278,0.0001764407,0.0001707609,0.0003402639,0.0005180326,0.0003818603,0.0003681126,0.001033125],"category_scores_gemma":[0.0003295829,0.0002058366,0.0001524406,0.0001525577,0.0003819466,0.0004521234,0.0002987891,0.0005836517,0.0005557866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005677233,"about_ca_system_score_gemma":0.0001988878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001047758,"about_ca_topic_score_gemma":0.001325147,"domain_scores_codex":[0.9999291,0.000006976093,0.000005935181,0.00002474334,0.00002391454,0.000009249467],"domain_scores_gemma":[0.999872,0.00002027072,0.00002860684,0.00002052986,0.00003035382,0.00002822883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000108687,0.00001589767,0.001257788,0.00005294167,0.00001344274,0.0001095529,0.00009834034,0.0005468787,0.995007,0.0006007442,0.0001242426,0.002064391],"study_design_scores_gemma":[0.00008451158,0.0004350352,0.1308932,0.0001820874,0.000152195,0.003137924,0.0007435285,0.02304241,0.7983873,0.002039899,0.04084219,0.00005975385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844946,0.002020706,0.009975063,0.0001317344,0.00003178234,0.00001287145,0.0004669338,0.00009781801,0.002768372],"genre_scores_gemma":[0.9765639,0.001392917,0.01801857,0.00009817444,0.00001352516,0.00003119137,0.002205897,0.00007141245,0.00160433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047758,"threshold_uncertainty_score":0.004119098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03803008848626927,"score_gpt":0.3300717137569915,"score_spread":0.2920416252707222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}