{"id":"W2096348473","doi":"10.1099/mic.0.025445-0","title":"A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1","year":2009,"lang":"en","type":"article","venue":"Microbiology","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Francisella; Mutant; Replication (statistics); Cell biology; Intracellular; Biology; Chemistry; Microbiology; Virology; Francisella tularensis; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005156077,0.0003264153,0.0002163569,0.0001700503,0.0001148535,0.0001850875,0.0001737105,0.0002494558,0.0007319818],"category_scores_gemma":[0.0001538677,0.0001216682,0.0001230901,0.0001059078,0.0001577807,0.0001096467,0.000164493,0.000327042,0.0003256674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631104,"about_ca_system_score_gemma":0.0001860449,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001688097,"about_ca_topic_score_gemma":0.001644832,"domain_scores_codex":[0.9999068,0.00001037931,0.00001083594,0.00001770328,0.0000347343,0.00001960748],"domain_scores_gemma":[0.9998451,0.00003688636,0.0000339769,0.00002592494,0.00002191129,0.00003611032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002248921,0.000007969433,0.00008051859,0.000005778769,7.014341e-7,0.00003035827,0.000006036896,0.00001550907,0.9995744,0.00002176299,0.000007752452,0.000226738],"study_design_scores_gemma":[0.000005363529,0.0001056619,0.004239893,0.000003665032,0.000005619092,0.0003506165,0.00004022658,0.0007109348,0.9938114,0.00002742223,0.0006940365,0.000005310422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979532,0.0001181147,0.00120581,0.00003721958,0.000007932217,0.000006055359,0.0002085884,0.00003493626,0.0004281987],"genre_scores_gemma":[0.9948556,0.0001203676,0.001466825,0.00002275861,0.000003127424,0.00001837993,0.0006252296,0.00003442019,0.002853254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688097,"threshold_uncertainty_score":0.003356576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007470317153606501,"score_gpt":0.2180645415133109,"score_spread":0.2105942243597044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}