{"id":"W2096357680","doi":"10.1093/mutage/gen048","title":"Effects of hTERT on genomic instability caused by either metal or radiation or combined exposure","year":2008,"lang":"en","type":"article","venue":"Mutagenesis","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Genome instability; Telomerase reverse transcriptase; Telomerase; Carcinogenesis; Cancer research; Telomere; Clonogenic assay; Chemistry; Molecular biology; Biology; Cell culture; DNA damage; Cell biology; Genetics; Gene; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001524226,0.0002341356,0.0005457874,0.0001233641,0.0000974685,0.000005773466,0.0001174378,0.000133153,0.0003996302],"category_scores_gemma":[0.0002514609,0.0001609753,0.0001273652,0.0003013407,0.0001215216,0.00006748297,0.00002347782,0.000102124,0.00004686361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001153467,"about_ca_system_score_gemma":0.0002168143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001646049,"about_ca_topic_score_gemma":0.00003101427,"domain_scores_codex":[0.9985244,0.0001399532,0.0003790821,0.000365621,0.0003278481,0.0002631521],"domain_scores_gemma":[0.9989229,0.0002901651,0.0001327607,0.0004344848,0.00006671087,0.0001529455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005324346,0.001645988,0.1128232,0.0007892705,0.0003386123,0.0004332816,0.002141362,0.000009932462,0.8495239,0.000009987765,0.002297279,0.02466283],"study_design_scores_gemma":[0.003719076,0.001462428,0.5364572,0.00004263403,0.000152117,0.00002420013,0.00005267422,0.0000488679,0.4560863,0.000002147279,0.001773796,0.000178562],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980437,0.0005469151,0.00006356938,0.0001790125,0.0002077821,0.0007452949,0.00002871078,0.00008814805,0.000096838],"genre_scores_gemma":[0.9964107,0.0002747067,0.0001757259,0.0004465538,0.00007788176,0.00003432231,0.00003708491,0.00004179283,0.002501188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.423634,"threshold_uncertainty_score":0.6564382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01959927547185221,"score_gpt":0.2474351674849968,"score_spread":0.2278358920131446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}