{"id":"W2096369318","doi":"10.1152/ajpheart.01205.2005","title":"Inhibition of phospholipase C-γ<sub>1</sub>augments the decrease in cardiomyocyte viability by H<sub>2</sub>O<sub>2</sub>","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Protein kinase C; Phospholipase C; Tyrosine phosphorylation; Biology; Gq alpha subunit; Phosphorylation; Phospholipase; Apoptosis; Viability assay; Internal medicine; Endocrinology; Molecular biology; Signal transduction; Cell biology; Biochemistry; G protein; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001114851,0.0004752013,0.0003045723,0.0001130378,0.0001129511,0.0002085157,0.0001307,0.0002067885,0.001434023],"category_scores_gemma":[0.00007669024,0.0001105068,0.0001904912,0.00007646853,0.0002153761,0.0001895457,0.0001788285,0.0005679057,0.0002936882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001726976,"about_ca_system_score_gemma":0.000156357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003219911,"about_ca_topic_score_gemma":0.0006805258,"domain_scores_codex":[0.9999387,0.00001051307,0.000005480974,0.00001181721,0.00001340132,0.00002014638],"domain_scores_gemma":[0.9999257,0.00001392268,0.00003064586,0.000007436242,0.000006191357,0.00001606929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002946073,0.00002952338,0.0001752409,0.00004371603,0.00000781895,0.00005548764,0.00001704196,0.00002984332,0.9982377,0.00002781947,0.00002418556,0.001056909],"study_design_scores_gemma":[0.00004300363,0.0009806866,0.00973092,0.00001204756,0.00002844085,0.000206602,0.00005841877,0.0003822771,0.9867185,0.00004271042,0.001790843,0.000005468231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936986,0.003133486,0.001761206,0.0001548304,0.00005276909,0.00002435102,0.0001793537,0.00005053436,0.0009449515],"genre_scores_gemma":[0.9941069,0.002542864,0.001137886,0.0001141733,0.00003127666,0.00003816705,0.0003332784,0.00001288497,0.001682564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434023,"threshold_uncertainty_score":0.00479728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004799419528067585,"score_gpt":0.217079802409801,"score_spread":0.2122803828817334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}