{"id":"W2096376623","doi":"10.1093/carcin/bgu016","title":"Targeted deletion of RasGRP1 impairs skin tumorigenesis","year":2014,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Carcinogenesis; Cancer research; Keratinocyte; Activator (genetics); Biology; Cell culture; Cancer; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001389678,0.0005789872,0.0003211979,0.0005988314,0.0001927653,0.0003282946,0.000334944,0.0005114955,0.002976832],"category_scores_gemma":[0.0001302356,0.0003189545,0.000337983,0.0002274702,0.0003246088,0.0002944093,0.0003236941,0.0009541516,0.0007412572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00028627,"about_ca_system_score_gemma":0.0002240636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005130799,"about_ca_topic_score_gemma":0.0006362131,"domain_scores_codex":[0.9997558,0.00003681699,0.00002757734,0.00004896306,0.00006538418,0.0000655057],"domain_scores_gemma":[0.9996955,0.000049124,0.00007477895,0.00003962816,0.00001363126,0.000127478],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001398575,0.00007572923,0.00008969737,0.00001542738,0.000005840559,0.00006917922,0.00001303715,0.0000918625,0.9987075,0.0001064111,0.00002518348,0.000660206],"study_design_scores_gemma":[0.00001917147,0.0005176995,0.00305625,0.000006587603,0.00002251879,0.0002715133,0.00004251802,0.001254647,0.9936343,0.00008701994,0.001081033,0.000006679554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963977,0.0004153133,0.001322462,0.00006731824,0.00003582569,0.0000250153,0.0003992327,0.0001951417,0.001141979],"genre_scores_gemma":[0.9949428,0.0003752719,0.0007661221,0.00002373409,0.000006453499,0.00002253359,0.0002794865,0.00003805893,0.003545474],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002976832,"threshold_uncertainty_score":0.009958506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006008155161474483,"score_gpt":0.2019179562737574,"score_spread":0.1959098011122829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}