{"id":"W2096376623","doi":"10.1093/carcin/bgu016","title":"Targeted deletion of RasGRP1 impairs skin tumorigenesis","year":2014,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Cancer Institute","keywords":"Carcinogenesis; Cancer research; Keratinocyte; Activator (genetics); Biology; Cell culture; Cancer; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002298739,0.0001614516,0.0002087264,0.00006532142,0.00005854165,0.000006619058,0.0001889609,0.0001401057,0.00004671552],"category_scores_gemma":[0.00008965531,0.0001546808,0.0001657101,0.0001166318,0.00005749814,0.000002414452,0.00006800195,0.00003063481,0.00001943855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001066642,"about_ca_system_score_gemma":0.00005352588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006122222,"about_ca_topic_score_gemma":0.00002111691,"domain_scores_codex":[0.9989529,0.0001034069,0.0002459922,0.0003179318,0.0001395412,0.0002401828],"domain_scores_gemma":[0.9992004,0.0000141843,0.0001066923,0.000450103,0.0001264587,0.0001021316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004586764,0.00003433478,0.02443299,0.00003756388,0.00002906103,0.000001149605,0.00002810137,0.00002838677,0.9675034,0.00020802,0.001262464,0.006388692],"study_design_scores_gemma":[0.0003375684,0.000343337,0.06371794,0.000006084535,0.00003289492,0.000009459271,0.00003378741,0.00007460999,0.9245971,0.00005685822,0.01061359,0.0001767395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924577,0.0007733341,0.00472412,0.00002252194,0.0001913739,0.0001260036,0.00002403026,0.00001794898,0.001662916],"genre_scores_gemma":[0.9983852,0.00007911701,0.0006240502,0.00009683901,0.0003229567,0.0000250264,0.0001439882,0.00002937277,0.0002934515],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04290624,"threshold_uncertainty_score":0.63077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006008155161474483,"score_gpt":0.2019179562737574,"score_spread":0.1959098011122829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}