{"id":"W2096504220","doi":"10.1242/jcs.01072","title":"Quantitative analysis of phagolysosome fusion in intact cells: inhibition by mycobacterial lipoarabinomannan and rescue by an 1α,25-dihydroxyvitamin D3–phosphoinositide 3-kinase pathway","year":2004,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Hospital and Health Sciences Centre; University of British Columbia","funders":"","keywords":"Lipoarabinomannan; Phagosome; Phagolysosome; Biology; Cell biology; Flow cytometry; Endocytic cycle; Phagocytosis; Molecular biology; Endocytosis; Biochemistry; Cell; Mycobacterium tuberculosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008209723,0.00106474,0.001004594,0.000657974,0.0003532644,0.0006446528,0.0007878236,0.00111001,0.0009528842],"category_scores_gemma":[0.000311819,0.0003419581,0.0006589379,0.0007932645,0.0004747665,0.0004729831,0.0005449309,0.001260077,0.0007736867],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007654309,"about_ca_system_score_gemma":0.0003825885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065093,"about_ca_topic_score_gemma":0.0009662589,"domain_scores_codex":[0.9991385,0.0001899171,0.0001054864,0.0001684807,0.0002346723,0.0001629855],"domain_scores_gemma":[0.9994231,0.0001691784,0.0001144959,0.0001013761,0.0001030984,0.00008879969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005980157,0.00002657003,0.00005819025,0.00003861691,0.000004686559,0.00001738908,0.00002593804,0.00003897126,0.9993929,0.00004949849,0.000006753184,0.0002806744],"study_design_scores_gemma":[0.000008825698,0.0001137896,0.001222968,0.00000348354,0.000008505126,0.00004782023,0.00002424003,0.001430634,0.9967584,0.00002735345,0.0003487226,0.00000525328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605716,0.002510195,0.03293603,0.0001037829,0.00006389407,0.0002360155,0.001794215,0.0004541042,0.001330095],"genre_scores_gemma":[0.9493386,0.001733257,0.04056664,0.00006954642,0.00002367313,0.0007554067,0.002639478,0.000150533,0.004722943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00111001,"threshold_uncertainty_score":0.005553603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030698857594163,"score_gpt":0.259855944151699,"score_spread":0.2495489555757573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}