{"id":"W2096543460","doi":"10.1186/1475-2867-6-25","title":"Stem cells, senescence, neosis and self-renewal in cancer.","year":2006,"lang":"en","type":"article","venue":"Cancer Cell International","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Cancer Centre; Windsor Clinical Research; Dalhousie University","funders":"","keywords":"Senescence; Biology; Cytokinesis; Genome instability; Cell biology; Telomere; Mitosis; Mitotic catastrophe; Chromosome instability; Stem cell; Cell division; Cancer cell; Genetics; DNA damage; Cancer; Cancer research; Cell; Gene; Chromosome; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004501319,0.0004462462,0.0005929032,0.001023869,0.0003763839,0.0008579771,0.0004145565,0.0009359181,0.001357614],"category_scores_gemma":[0.0002104063,0.0001183789,0.000239797,0.001239164,0.001076132,0.00110749,0.000675081,0.00138641,0.0006856246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006232032,"about_ca_system_score_gemma":0.0005764829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006216618,"about_ca_topic_score_gemma":0.001177196,"domain_scores_codex":[0.9998707,0.00002960667,0.0000147401,0.00001962276,0.00004954478,0.00001572517],"domain_scores_gemma":[0.9998708,0.00004562182,0.00002959504,0.000004499029,0.00002359756,0.00002596626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002142609,0.0001062912,0.001657529,0.008477653,0.00008045862,0.001879131,0.0009551532,0.00115087,0.03978227,0.174657,0.04476028,0.726279],"study_design_scores_gemma":[0.00001191078,0.0003038898,0.002794089,0.0007444409,0.00003841353,0.004220325,0.0002776544,0.0004271813,0.00512281,0.06800627,0.9180237,0.0000293174],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001342053,0.9923382,0.00088306,0.001549542,0.0009416369,0.000007456168,0.00002285747,0.00001405846,0.002901045],"genre_scores_gemma":[0.02009571,0.9674654,0.0012305,0.001739627,0.002683935,0.00002526013,0.00009683698,0.000007464361,0.006655182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001357614,"threshold_uncertainty_score":0.004541695,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01195568973299953,"score_gpt":0.2616813907194938,"score_spread":0.2497257009864943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}