{"id":"W2096543460","doi":"10.1186/1475-2867-6-25","title":"Stem cells, senescence, neosis and self-renewal in cancer.","year":2006,"lang":"en","type":"article","venue":"Cancer Cell International","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Cancer Centre; Windsor Clinical Research; Dalhousie University","funders":"","keywords":"Senescence; Biology; Cytokinesis; Genome instability; Cell biology; Telomere; Mitosis; Mitotic catastrophe; Chromosome instability; Stem cell; Cell division; Cancer cell; Genetics; DNA damage; Cancer; Cancer research; Cell; Gene; Chromosome; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007099134,0.0001757995,0.0002232345,0.0001192478,0.00004310189,0.00003358461,0.000136535,0.00008830646,0.0005681512],"category_scores_gemma":[0.000001611934,0.0001690777,0.00005311672,0.0001613931,0.0000581415,0.0001237398,0.00004563158,0.0001445597,0.00001317179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004475946,"about_ca_system_score_gemma":0.0002025077,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01154762,"about_ca_topic_score_gemma":0.0040313,"domain_scores_codex":[0.9987398,0.00001961247,0.000289542,0.0003702055,0.0003215057,0.000259296],"domain_scores_gemma":[0.999513,0.00003460555,0.00008982156,0.0001418071,0.0001161944,0.0001045787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002452346,0.0008357653,0.8475949,0.0002605806,0.00009935138,0.0001746091,0.000718557,0.0003407049,0.1096309,0.0005348715,0.01304097,0.02652355],"study_design_scores_gemma":[0.008041278,0.0002207427,0.3488075,0.000803386,0.0002061724,0.00008456926,0.0007794053,0.00911904,0.3981284,0.0002286154,0.2324435,0.001137307],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806167,0.005789132,0.0000549281,0.001059757,0.001280305,0.0002242037,0.00006737358,0.00008194539,0.01082559],"genre_scores_gemma":[0.9866302,0.004986895,0.0003871072,0.0004985985,0.000680159,0.0000685418,0.00002128679,0.00002337826,0.006703809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4987874,"threshold_uncertainty_score":0.9950346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01195568973299953,"score_gpt":0.2616813907194938,"score_spread":0.2497257009864943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}