{"id":"W2096606886","doi":"10.1038/cdd.2008.29","title":"Bax siRNA promotes survival of cultured and allografted granule cell precursors through blockade of caspase-3 cleavage","year":2008,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Région Normandie; Institut National de la Santé et de la Recherche Médicale","keywords":"Transplantation; Small interfering RNA; Apoptosis; Cell biology; Ex vivo; Caspase; Programmed cell death; Biology; Bcl-xL; Ceramide; Caspase 3; Transfection; In vitro; Chemistry; Cell culture; Biochemistry; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004791739,0.0006050579,0.0006550071,0.0004615511,0.0003523534,0.0006878088,0.0003899435,0.000460822,0.002219157],"category_scores_gemma":[0.0002467289,0.0002537789,0.0004855104,0.0002669562,0.0005008586,0.0005328194,0.0003157294,0.002002051,0.0006349652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004577355,"about_ca_system_score_gemma":0.0005240868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004676388,"about_ca_topic_score_gemma":0.001029845,"domain_scores_codex":[0.9994729,0.00007558999,0.00008947858,0.00009237954,0.0001316019,0.0001380324],"domain_scores_gemma":[0.9994928,0.000169322,0.00009969812,0.00006748949,0.0000436065,0.0001270652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003515454,0.00005688416,0.00009399789,0.00003999664,0.000008329677,0.00006628979,0.00003991453,0.00005447719,0.9982151,0.0001567339,0.00004632621,0.0008704123],"study_design_scores_gemma":[0.00002688446,0.0001723656,0.0008383112,0.000003025708,0.00001426963,0.000115123,0.00002063327,0.0003541313,0.9978918,0.0000304262,0.0005306324,0.00000236172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916796,0.001167309,0.004753669,0.0002209414,0.0001030218,0.0000431628,0.0003074895,0.000234252,0.001490606],"genre_scores_gemma":[0.9919543,0.0006704153,0.003339346,0.00005859544,0.00002938022,0.00005846599,0.0004009705,0.00006940267,0.003419182],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002219157,"threshold_uncertainty_score":0.007423878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01441325681752737,"score_gpt":0.2181231651326347,"score_spread":0.2037099083151074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}