{"id":"W2096660216","doi":"10.1089/jir.2012.0141","title":"Small Interfering RNA-Mediated Knockdown of Chicken Interferon-γ Expression","year":2013,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Gene knockdown; RNA interference; Small interfering RNA; Biology; Gene silencing; Interferon; Transfection; Downregulation and upregulation; Dicer; Molecular biology; Cell biology; RNA; Cell culture; Gene; Virology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003718515,0.0005401867,0.0005674323,0.0002455136,0.0002338806,0.0003872839,0.0004569531,0.0004705063,0.001128143],"category_scores_gemma":[0.0001570415,0.0002729529,0.000463379,0.0002181006,0.0003801749,0.0001957051,0.0002226366,0.0008712009,0.0004935252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000484851,"about_ca_system_score_gemma":0.0004361731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001292367,"about_ca_topic_score_gemma":0.002139816,"domain_scores_codex":[0.9995809,0.0000448038,0.00006633841,0.0001313008,0.0001114626,0.00006522944],"domain_scores_gemma":[0.9998596,0.00004144644,0.00003259581,0.00001789784,0.00002752961,0.00002097327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000421974,0.00001294174,0.00003772377,0.00006418375,0.000004537838,0.00002946668,0.00002195509,0.00004903188,0.9988855,0.0001041947,0.00005221308,0.0006961027],"study_design_scores_gemma":[0.00002546764,0.0002195265,0.001101731,0.00001043575,0.00003408565,0.0001302425,0.00002574959,0.001554746,0.9907876,0.00002914535,0.006074326,0.000006919136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9370263,0.005568601,0.04351414,0.0003637915,0.000435389,0.0007736905,0.002761031,0.0005442298,0.00901284],"genre_scores_gemma":[0.9337152,0.004911894,0.04258548,0.0002951372,0.00004765348,0.0009185959,0.00280475,0.0001345667,0.01458691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292367,"threshold_uncertainty_score":0.003773987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05780028551932072,"score_gpt":0.3210386736903255,"score_spread":0.2632383881710048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}