{"id":"W2096676063","doi":"10.1016/j.regpep.2005.01.004","title":"Interleukin-1β depolarizes magnocellular neurons in the paraventricular nucleus of the hypothalamus through prostaglandin-mediated activation of a non selective cationic conductance","year":2005,"lang":"en","type":"article","venue":"Regulatory Peptides","topic":"Neuroendocrine regulation and behavior","field":"Psychology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Queen's University","funders":"","keywords":"Hypothalamus; Internal medicine; Endocrinology; Depolarization; Chemistry; Reversal potential; Oxytocin; Vasopressin; Median eminence; Tetrodotoxin; Membrane potential; Magnocellular cell; Corticotropin-releasing hormone; Patch clamp; Biophysics; Biology; Electrophysiology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001640048,0.0001862761,0.0002536943,0.0001049705,0.00008562671,0.00001609394,0.0003474108,0.00007076083,0.00009924285],"category_scores_gemma":[0.000079491,0.0001245676,0.0001376444,0.0006069801,0.0002475673,0.0001847643,0.00004058017,0.0002479702,0.00001495291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008237478,"about_ca_system_score_gemma":0.00007342345,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001052904,"about_ca_topic_score_gemma":0.00007100536,"domain_scores_codex":[0.9982578,0.0003535851,0.0005061341,0.0003027391,0.0003222383,0.0002575138],"domain_scores_gemma":[0.9986491,0.0002035985,0.0004256441,0.0005846487,0.0001101909,0.00002685773],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003194964,0.00183508,0.314506,0.0001178669,0.0001321678,0.00003497059,0.01326598,0.0005785787,0.6541106,0.008564475,0.003078926,0.003455877],"study_design_scores_gemma":[0.001061621,0.0001115542,0.8230483,0.00005846719,0.0000496887,0.00007014444,0.0006644941,0.0001111361,0.1717471,0.0001895452,0.002754978,0.000132938],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972097,0.0001395868,0.00002931534,0.001066085,0.0001273291,0.0008414146,0.00001796343,0.00002406382,0.0005445834],"genre_scores_gemma":[0.9989223,0.000005449732,0.00009792676,0.0001750049,0.0000674842,0.00007679667,0.00001400056,0.00002545306,0.0006155371],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5085423,"threshold_uncertainty_score":0.5079721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0242608558365354,"score_gpt":0.2865985921548753,"score_spread":0.2623377363183398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}