{"id":"W2096759887","doi":"10.3945/jn.112.159079","title":"Application of Key Events Dose Response Framework to Defining the Upper Intake Level of Leucine in Young Men","year":2012,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; University of Alberta","funders":"","keywords":"Leucine; Ingestion; Toxicity; Event (particle physics); Adverse effect; Set (abstract data type); Physiology; Key (lock); Medicine; Internal medicine; Toxicology; Biology; Biochemistry; Amino acid; Computer science; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008555924,0.00006082906,0.000122992,0.00007167651,0.00001938295,0.000003131986,0.0001366831,0.0001022899,0.000003538509],"category_scores_gemma":[0.0003421366,0.00004596646,0.00006077145,0.0001309842,0.00002284766,0.000009781947,0.00003013647,0.0001153179,0.000001078962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002697002,"about_ca_system_score_gemma":0.00004129024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009339559,"about_ca_topic_score_gemma":0.000002309051,"domain_scores_codex":[0.9992468,0.0001057367,0.0003511879,0.00006321405,0.000133483,0.00009962692],"domain_scores_gemma":[0.9993419,0.00004755566,0.0002880345,0.0001326256,0.0001530618,0.00003678862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001439874,0.0002849571,0.0458838,0.00006715348,0.00002213138,3.383969e-7,0.0004275645,0.0000562678,0.9498636,0.0002338335,0.0003059304,0.00141453],"study_design_scores_gemma":[0.0008793562,0.0004379775,0.1743538,0.0002782372,0.00002506053,0.00006086182,0.0006129047,0.00001276532,0.8204969,0.0009096022,0.001856088,0.00007646927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819232,0.001865153,0.01563451,0.0003125813,0.000066899,0.0001075825,0.00000668035,6.566231e-7,0.00008276328],"genre_scores_gemma":[0.9940671,0.0003012698,0.005375742,0.00004334156,0.0001667705,0.000009714952,0.000007555254,0.000007370384,0.00002108582],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1293667,"threshold_uncertainty_score":0.1874458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01976958523470559,"score_gpt":0.2940663270577137,"score_spread":0.2742967418230081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}