{"id":"W2096852211","doi":"10.1002/chem.200903207","title":"Putative One‐Pot Prebiotic Polypeptides with Ribonucleolytic Activity","year":2010,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"European Social Fund; Generalitat de Catalunya","keywords":"Peptide; Chemistry; Amino acid; Prebiotic; RNA; Stereochemistry; Folding (DSP implementation); Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001229125,0.0003059772,0.0002498149,0.0001025536,0.0001116144,0.0003104213,0.0002341677,0.0003211835,0.0007537567],"category_scores_gemma":[0.0001975139,0.0001560779,0.0003312853,0.0001291375,0.0002458671,0.000244397,0.0002417213,0.0004856687,0.0003601814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002202392,"about_ca_system_score_gemma":0.0001035005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001338108,"about_ca_topic_score_gemma":0.0001545993,"domain_scores_codex":[0.9999034,0.00001338521,0.000007199324,0.00002420952,0.00002796669,0.00002375246],"domain_scores_gemma":[0.9998295,0.0000306565,0.00006182658,0.00002328552,0.00002159887,0.00003302213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000227564,0.00000680913,0.0002099094,0.00002298875,0.000005098262,0.00003812387,0.00001083254,0.00004018754,0.9989957,0.00004918717,0.00000800763,0.0005903392],"study_design_scores_gemma":[0.000007862545,0.0002082022,0.005418021,0.000003171948,0.00001807729,0.0004846168,0.00003478646,0.0005755817,0.9918515,0.0000658873,0.001325563,0.000006798316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962132,0.0006178968,0.002170087,0.00003187293,0.00001097271,0.00001392124,0.0001147072,0.00003652431,0.000790906],"genre_scores_gemma":[0.9957325,0.0001821839,0.002345557,0.00002947345,0.000004198167,0.0000185128,0.0004863382,0.00002413425,0.00117722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007537567,"threshold_uncertainty_score":0.002521574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009105993654489528,"score_gpt":0.2083712052211333,"score_spread":0.1992652115666437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}