{"id":"W2096885361","doi":"10.1016/j.jtbi.2005.03.034","title":"A mathematical model of hematopoiesis: II. Cyclical neutropenia","year":2005,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Blood disorders and treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"Haematopoiesis; Neutropenia; Cyclic neutropenia; Granulocyte; Chronic myelogenous leukemia; Oscillation (cell signaling); Biology; Leukemia; Immunology; Granulocyte colony-stimulating factor; Internal medicine; Medicine; Stem cell; Chemotherapy; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009826523,0.0004670366,0.0006664542,0.000549509,0.0005689508,0.001547572,0.001308259,0.001594231,0.003085001],"category_scores_gemma":[0.00417879,0.0002947233,0.0006993835,0.0006197285,0.001662445,0.001666779,0.001113397,0.001500062,0.0002642945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001384548,"about_ca_system_score_gemma":0.001361195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003511463,"about_ca_topic_score_gemma":0.00167345,"domain_scores_codex":[0.9996427,0.0001529864,0.0000130286,0.00004048824,0.00008058187,0.00007024435],"domain_scores_gemma":[0.9988257,0.0005848574,0.0002385472,0.00006594195,0.0001135335,0.0001713431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00002967941,0.00003539331,0.0005891874,0.00005073233,0.00001428541,0.0002051781,0.00008635277,0.1371753,0.000737681,0.85605,0.001998444,0.003027843],"study_design_scores_gemma":[0.00004231335,0.0000377371,0.0002612522,0.00001921304,0.00001429682,0.0002483417,0.00003959833,0.6733168,0.0001173682,0.3238857,0.002001642,0.00001576703],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2672689,0.006739679,0.5942615,0.02186139,0.0006066902,0.0001421249,0.0008896329,0.0002056316,0.1080244],"genre_scores_gemma":[0.9637348,0.002273391,0.01640222,0.0007419818,0.0003376247,0.0001499557,0.0001269347,0.00004186063,0.01619121],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003511463,"threshold_uncertainty_score":0.01032031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007542302302799849,"score_gpt":0.2596358833056017,"score_spread":0.2520935810028019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}